Printer Friendly

Wrinkles and Retin-A.

Wrinkles and Retin-A

Tretinoin (brand name Retin-A) -- the prescription anti-acne ointment that appears to reverse signs of skin aging -- reduces wrinkles, softens skin and lightens pigment spots for at least 16 months in patients who continue using the cream, researchers report.

"What we find in general is that the longer we go, the more improvement we get," says John Voorhees, chairman of the department of dermatology at the University of Michigan Medical Center in Ann Arbor. Voorhees coauthored the original, widely reported, four-month study in the Jan. 22 JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, in which Retin-A use was associated with "significant improvement" in sun-damaged or "photoaged" skin (SN: 1/30/88, p.71). He and other researchers presented new data last week in Philadelphia at a conference on skin aging at Jefferson Medical College.

So far, Voorhees says, the most serious side effect is transient skin irritation, which usually subsides "after a couple of weeks." Long-term toxicity, however, has yet to be determined. Also unknown: how the cream works, what the minimum effective dose is, how long the benefits may last after treatment stops and whether the drug helps prevent skin cancer.
COPYRIGHT 1988 Science Service, Inc.
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 1988, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

Article Details
Printer friendly Cite/link Email Feedback
Title Annotation:anti-acne ointment
Publication:Science News
Date:May 28, 1988
Previous Article:Storms at the bottom of the sea.
Next Article:Cell receptors drop with HIV infection.

Related Articles
Acne drug smooths wrinkles.
Wrestling with wrinkles: scientists are closing in on the secrets of skin aging.
Tretinoin: lasting results, lingering doubts.
Water-soluble vitamin A shows promise.
Acne cream works as spot remover.
Drug fiends: even inside Johnson & Johnson, public safety can take a back seat to profits.
Ortho sentenced for obstruction of justice.
Here comes the sun ... and wrinkles.
The skin game. (Special Feature).

Terms of use | Copyright © 2017 Farlex, Inc. | Feedback | For webmasters