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WEX TECHNOLOGIES INC.-PACLITAXEL UPDATE

 VANCOUVER, British Columbia, Nov. 30 /PRNewswire/ -- In a press release dated Nov. 3, 1993, WEX Technologies Inc. (OTC Bulletin Board: WEXTF; Alberta: WXT) announced that it has signed a letter of agreement dated Oct. 9, 1993, with Professor Zheng of an Institute in China, regarding cooperation on a project for the development and production of Paclitaxel (Taxol(R)). WEX was provided with two samples for testing, one from natural sources and a second from the plant-cell method. These samples were sent for testing to the Department of Botany, University of British Columbia, under the supervision of Dr. G.H.N. Towers, F.R.S.C., Professor Emeritus. Analysis of High Performance Liquid Chromatography (HPLC), mass spectra and HMNR data confirmed unequivocally that the samples are Paclitaxel.
 The purity of the Paclitaxel produced from natural sources was 82.7 percent pure. The major impurities were unidentified. The minor contaminants were very low levels of baccatin III, brevifoliol, 10 deacetyltaxol and a trace of cephalomannine. The purity of Paclitaxel produced by the plant cell culturing method was 92.4 percent pure and contained small amounts of baccatin III, brevifoliol and 10-deacetyltaxol.
 The presence of these types of contaminants in both samples confirms that the materials originate from extracts of Yew (Taxus species).
 Based upon these results, the company will prepare and execute a production contract with the Zheng group in order to secure the worldwide right to these methods of producing Paclitaxel. Production output from these sources is estimated as follows:
 -- From natural sources, 2.5 kg in 1994; 5 kg in each year from 1995
 to 1997; and
 -- From cultured sources, 1 kg in 1995; 5 kg in 1996; 10 kg in 1997.
 The market price of Taxol(R) rose last year from $250,000 per kilogram to over $3,000,000 per kilogram after FDA approval.
 -0- 11/30/93
 /CONTACT: Manfred Kurschner, 604-273-8081, or investors relations, 800-223-2839/
 (WEXTF)


CO: WEX Technologies Inc. ST: British Columbia IN: MTC SU:

JB-JL -- LA030 -- 8850 11/30/93 15:25 EST
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Publication:PR Newswire
Date:Nov 30, 1993
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