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Vitamin D relieves menstrual symptoms.

A letter published in the Archives of Internal Medicine reported the results of a study of women with primary dysmenorrhea which found that a single high dose of oral vitamin D3 reduced pain over a two month period.*

Italian researchers enrolled forty women who reported at least four painful periods over the previous six months and whose serum vitamin D levels were lower than 18 ng/mL. Twenty participants were administered 300,000 IU vitamin D3 five days before the beginning of their next menstrual cycle, while the remainder received a placebo. Pain symptoms were scored before treatment and at one and two months.

Women who received vitamin D3 reported a reduction in pain over two months compared to the placebo group. While 40% of subjects who received a placebo took drugs for pain at least once over the course of the trial, none who received vitamin D reported needing the drugs.



* Arch Intern Med. 2012 Feb 27;172(4):366-7.

Editor's Note: In an invited commentary in the journal, Elizabeth R. Bertone-Johnson, ScD and JoAnn E. Manson, MD, remark that it is important to determine how long a reduction in pain in association with a single dose of vitamin D would last. They note that, "If 300,000 IU is required every two months, this would equate to approximately 5,000 IU/day, considerably higher than the tolerable upper intake level set by the Institute of Medicine of 4,000 IU/day."

--D. Dye

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Title Annotation:IN THE NEWS
Author:Dye, D.
Publication:Life Extension
Article Type:Brief article
Geographic Code:1USA
Date:Jun 1, 2012
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