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VLP Therapeutics awarded Phase 1 SBIR grant to support novel virus-like particle vaccine-based cancer immunotherapy.

M2 PHARMA-October 12, 2017-VLP Therapeutics awarded Phase 1 SBIR grant to support novel virus-like particle vaccine-based cancer immunotherapy

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Biotechnology company VLP Therapeutics LLC reported on Wednesday the receipt of USD298,729 Phase I grant from the National Cancer Institute under auspices of the Small Business Innovation Research (SBIR) programme of the National Institutes of Health.

Under the Award Number R43CA217445, the SBIR Phase I grant will focus on "the development of a novel Virus-Like Particle vaccine-based cancer immunotherapy targeting PD-L1" as well as explore broader immune checkpoint inhibition mechanisms, added the company.

The company will use the SBIR grant to support its collaboration with Louis M Weiner, MD, director of the Georgetown Lombardi Comprehensive Cancer Center at Georgetown University.

According to the company, the research will focus on determining immune response in mice and includes support for proof-of-concept studies at the Georgetown Lombardi. Weiner, an expert in cancer immunotherapeutics, is an unpaid member of the VLP Scientific Advisory Board.

Unlike traditional vaccines, the company's novel, proprietary virus-like particles are identical to the authentic native viruses in their shapes, but do not carry the genetic material of native viruses. Hence, when the virus-like particles are presented within our bodies, the immune system will recognise the particles as foreign objects, triggering effective immune responses, concluded the company.

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Date:Oct 12, 2017
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