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Use nitropropanol, other compounds to control pathogenic bacteria.

USDA-ARS scientists have developed a method for controlling foodborne enteric bacterial pathogens in animals. These types of pathogens, which include Campylobacter spp., E. coli 0157:H7, L. monocytogenes and Salmonella spp., can be transmitted to humans who consume contaminated meat and poultry products.

Meat and poultry contamination often is caused by exposure of animal carcasses to ingested or fecal material during or after slaughter. This technology helps reduce bacterial pathogens by using an effective mixture of organic nitro-based compounds. Pharmaceutical companies and feed manufactures will be able to use this technology. Its advantages: its effects are longer-lasting than other techniques, and the compounds can be added to feed.

The compounds can be administered orally or externally before the animals are slaughtered, reducing the bacterial populations that may be present as contaminants in the gastrointestinal track or on the animal's skin. This approach can be used to treat meat-producing ruminant and non-ruminant animals, such as cattle, chickens, turkeys, ducks, quail, geese, pigs and sheep. Any transfer of the technology to industry will require a USDA Cooperative Research and Development Agreement.

Patent.-7,176,244. Use of 2-nitropropanol, 2-nitroethane, and 2-nitroethanol for control of microbial pathogens. Issued Feb. 13, 2007. Inventors: Robin Anderson, et al. Assigned to USDA. This patent covers a method and compositions for controlling foodborne enteric bacterial pathogens in animals. Populations of enteropathogenic bacteria may be substantially reduced or eliminated by treating animals with an effective amount of 2-nitropropanol, 2-nitroethane or 2-nitroethanol. The compounds may be administered orally, providing a reduction in the populations of the enteropathogenic bacteria in the alimentary tract of the animal. Or they may be applied externally onto the animal to reduce the populations of any bacteria that may be present as contaminants on the surface of the animal. The method and compositions are particularly useful for controlling Salmonella, enteropathogenic E. coli, Campylobacter and L. monocytogenes.

Further information. Robin Anderson, USDA-ARS Food and Feed Safety Research, 2881 F&B Rd., College Station, TX 77845; phone: 979-260-9317; fax: 979-260-9332;
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Publication:Microbial Update International
Date:Aug 1, 2008
Previous Article:Apply electron beam irradiation to reduce microbial counts in poultry.
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