Printer Friendly

Trichomoniasis-causing organism is sequenced.

Scientists have taken a first read of the genetic sequence of the organism responsible for a sexually transmitted infection called trichomoniasis.

This disease is caused by the single-celled parasite Trichomonas vaginalis. Symptoms of infection include discharges from the penis or vagina and burning and itching of the genitals.

Because the infection affects about 170 million people worldwide and can increase susceptibility to other sexually transmitted infections, such as with the AIDS virus, scientists worldwide saw a need for learning T. vaginalis' genetic code, says Jane Carlton of New York University School of Medicine. She and other researchers from 10 countries collaborated to sequence a draft of the genome.

The scientists used a method called whole-genome-shotgun sequencing. They cut the organism's six chromosomes into fragments, sequenced just the fragment ends, and then used a computer program to virtually patch together these bits.

By poring over this new information, the researchers identified several genes probably involved in the organism's ability to adhere to the vaginal wall and fight off a person's immune system, the team reports in the Jan. 12 Science. Crafting drugs that target proteins from these genes could offer new ways to fight the infection, Carlton says.
COPYRIGHT 2007 Science Service, Inc.
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2007, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

Article Details
Printer friendly Cite/link Email Feedback
Title Annotation:BIOLOGY
Publication:Science News
Date:Jan 27, 2007
Previous Article:Aquatic non-scents: repercussions of water pollutants that mute smell.
Next Article:Aging vets take stress disorder to heart.

Related Articles
Of vaginitis and sexual selection.
Genetic trickery probes tropical parasites.
Long-awaited bacterial genome debuts.
Know Your Enemy: Sequencing Pathogenic Microbes.
Kibble for thought: dog diversity prompts new evolution theory.
The year of the rat.
The path to species comparison.
National Center for Biotechnology Information.
Chlamydialike organisms and atherosclerosis.

Terms of use | Privacy policy | Copyright © 2021 Farlex, Inc. | Feedback | For webmasters