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Transfusion Therapy: Clinical Principles and Practice, 2nd Edition.

Transfusion Therapy: Clinical Principles and Practice, 2nd Edition. Paul D. Mintz, editor. Bethesda, MD: AABB Press, 2005, 690 pp., $185.00, hardcover. ISBN 1-56395-185-1.


This excellent book immediately throws the reader into the "pointy end" of transfusion practice-clinical decision making at the bedside. The first 11 chapters cover a range of clinical areas and conditions in which transfusion frequently plays a primary or supportive role. The first chapter in particular, Component Therapy before Bedside Procedures, by Walter Dzik, challenges us to consider the evidence for our practice and the assumptions we make. The recommendation for prospective controlled trials in this area, echoed by many authors throughout the book, provides transfusionists of today and tomorrow with a worthy goal.

The book comprises 27 chapters by 37 distinguished authors and is divided into 4 sections covering The Use of Blood Components in Clinical Practice, Blood Components and Derivatives, Adverse Events, and Quality in Transfusion Practice. The section on quality contains a well-written chapter on Administration of Blood Components, a recognized area of transfusion error. Mintz looks beyond North America with a comprehensive chapter entitled European Hemovigilance, written by colleagues in the United Kingdom and The Netherlands.

There is a diverse audience for this type of book, and there truly is "something in it for everyone". Clinicians involved in taking care of patients receiving blood products will find a wealth of information, including assistance in making the decision to transfuse, choosing the appropriate product, and recognizing and managing adverse reactions. Transfusion medicine specialists and trainees will also find a wealth of information. Each chapter is well referenced so that the reader is led to a comprehensive overview of selected areas of transfusion practice.

Like the first edition, this book is an excellent source of practical information for all those involved in transfusion practice. For the laboratory scientist, it provides an insight into clinical decision making. Given the lack of definitive evidence for much transfusion decision making, the laboratory scientist is given some understanding of why there is widespread variation in transfusion practice.

This book is an essential addition to the library of transfusion medicine specialists and would be worthwhile reading for all clinicians who prescribe blood products.

Helen Savoia

The Royal Children's Hospital

Parkville, Victoria 3050, Australia

DOI: 10.1373/clinchem.2005.054874
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Author:Savoia, Helen
Publication:Clinical Chemistry
Date:Jan 1, 2006
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