Printer Friendly

Toxicologic pathology; nonclinical safety assessment.

9781439872109

Toxicologic pathology; nonclinical safety assessment.

Ed. by Pritam S. Sahota, James A. Popp, Jerry F. Hardisty and Chirukandath Gopinath.

CRC Press

2013

999 pages

$259.95

Hardcover

RA1211

Pathologists Sahota, Popp, Hardisty, and Gopinath compile 21 chapters by academics and industry professionals from the US and Europe, who discuss nonclinical safety assessment for students, residents, toxicologists, pathologists, and toxicologic pathologists working in pharmaceutical drug research, to demonstrate pharmacological or off-target effects and improve the quality of drug safety evaluation. They begin with concepts in drug development--its stages, nonclinical safety evaluation, toxicokinetics, toxicologic pathology and routine and special techniques, principles of clinical pathology, toxicogenomics, and spontaneous lesions in control animals used in toxicity studies--then address pathological changes related to toxicity in each organ system, and their implications in the drug development process. Light microscopic and electron microscopic descriptions of lesions, differential diagnoses, biological consequences, pathogenesis, mechanisms of lesion formation, and the expected clinical pathology correlates are described.

([c] Book News, Inc., Portland, OR)

COPYRIGHT 2013 Book News, Inc.
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2013 Gale, Cengage Learning. All rights reserved.

Article Details
Printer friendly Cite/link Email Feedback
Publication:Reference & Research Book News
Article Type:Brief article
Date:Jun 1, 2013
Words:163
Previous Article:Fusion protein technologies for biopharmaceuticals; applications and challenges.
Next Article:Understanding diabetes; a biochemical perspective.
Topics:

Terms of use | Privacy policy | Copyright © 2019 Farlex, Inc. | Feedback | For webmasters