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Tocomin SupraBio boosts immune response in humans.

Tocomin SupraBio bioenhanced palm tocotrienol complex from Carotech Inc. improved immune response and function in healthy women volunteers post vaccination, according to a study published in the European Journal of Clinical Nutrition.

This randomized, double-blind, placebo-controlled human trial evaluated potential effects of palm tocotrienol complex during immunization. A total of 108 healthy, non-smoking women aged 18-25 years were recruited for this study. Randomly assigned to two groups, volunteers in the supplemented group were given 200 mg of palm tocotrienol complex or soy oil (placebo) capsules two times per day for two months.

The palm tocotrienol capsules were manufactured by Hovid Berhad and contained Tocomin SupraBio (62 mg alpha-to-cotrienol, 113 mg gamma-tocotrienol, 26 mg delta-tocotrienol and 92 IU of alpha-tocopherol).

Blood samples were taken and analyzed at 0, 28 and 56 days. On Day 28 volunteers received a single shot of tetanus toxoid (TT) vaccine after their blood was drawn. Subsequent blood tests at the end of the study period (Day 56) revealed that levels of anti-TT antibody, interferon (IFN)-[gamma] and interleukin (IL)-4 in the supplemented group were significantly elevated post vaccination compared to the control group. Increased production of IFN-[gamma] and lL-4 indicates a positive cell-mediated immune response leading to higher concentration of anti-TT lgG antibody. At the same time, production of pro-inflammatory marker interleukin (IL)-6 in the supplemented group was significantly suppressed compared to control. For further information:
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Title Annotation:Research Highlights
Publication:Nutraceuticals World
Date:Apr 1, 2011
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