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Timely Advice on Clearing Toxins: Detox with Oral Chelation: Protecting Yourself from Lead, Mercury, & Other Environmental Toxins.

David Brown's seventh book, coauthored with pioneer physician Garry Gordon, looks at one of the critical issues of our time: toxic minerals and their removal through noninvasive means.

Toxic mineral levels are 100 to 1000 times higher in people than they were a few centuries ago. Such minerals include lead, mercury, arsenic, cadmium, nickel, and aluminum. Over 400 tons of mercury plus hundreds of tons of other toxic minerals are added annually to the North American environment.

Toxic minerals can be removed by infusion of chelators and by whatever fraction of an oral chelator that gets taken up to cleanse the body. Chelators have negative charges in a geometry that matches divalent cationic minerals with variable affinity for specific toxic minerals. EDTA has highest affinity for lead. DMPS and DMSA have affinity for mercury. D-penicillamine is nonspecific and picks up all divalent cations. In addition, D-penicillamine binding constant is high enough that transfer of toxic minerals at cell junctions does not occur. As a nonmetabolized amino acid, D-penicillamine can move in and out of the brain as well as the cells. Following these functional protocols, clinicians gain predictive information about each individual's status and need for therapy.


Dr. Gordon has pioneered the use of oral EDTA for noninvasive chelation. However you do it, remove the lead and mercury as well as other toxic minerals. Fortunately, provocative tests for toxic minerals exist to find out individual risks. Hair tests screen for toxic minerals. DMSA, DMPS, EDTA, and D-penicillamine have been used for provocative tests to quantify body burden of toxic minerals. In addition, essential nutritional minerals can be assessed, but only by D-penicillamine.

During congressional hearings, when the pediatrician for the Centers for Disease Control was asked what she recommended when blood levels of mercury were elevated, she pointed out that "by the time the levels are detectable in the blood, damage to learning and function had already occurred."

As mentioned in the book, toxic minerals can also be removed by nature's detoxifiers; that is, by eating natural detoxifying foods. High-sulfur foods such as ginger, garlic, onions, broccoli sprouts, and eggs, as well as insoluble dietary fiber and ascorbate (vitamin C), help scavenge and safely remove from the body any toxic minerals that they contact. For example, each gram of ascorbate can remove 20 [micro]gm of toxic minerals. For typical people in industrial society, this means that 1 gram of ascorbate daily will help balance their daily toxic mineral exposure.

Healthy people produce metallothionein to trap and safely remove toxic minerals from the body, but people under stress or with nutritional deprivations "hunker down" and stop producing elective protective molecules like metallothionein. Then, and only then, do toxic minerals bioaccumulate. Then, and only then, do people need detoxification from toxic minerals. Given the distress, dietary deficits, and environmental exposures, the need for toxic mineral mitigation is pervasive.

With increasing links between toxic minerals in the body and chronic heart, vascular, brain, and developmental maladies, it is increasingly important to understand toxic minerals and what to do about them.

Abundantly referenced and with a useful section explaining technical terms, Detox with Oral Chelation is a clear discussion of the need for therapy to get toxic minerals out of the environment as well as the body. Clearly written, with practical advice to improve the health of the reader, Detox with Oral Chelation is a timely and worthy read. The first three appendices are interviews that David Brown conducted with his coauthor, with Leslie Hamud, and with Gerhard Schrauzer. Each one adds important details or background to the book.

by David Jay Brown and Garry Gordon, MD

Smart Publications, P.O. Box 4667, Petaluma, California 94955; fax: 888-998-6889;

Paperback; $17.95; [C]2009; 288 pp.
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Author:Brown, David Jay; Gordon, Garry
Publication:Townsend Letter
Article Type:Book review
Date:May 1, 2010
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