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Thrombotic lesion of saphenous vein graft resolved by antiaggregant therapy/ Antiagregan tedavi ile cozulen trombotik safen ven grefti lezyonu.

A 68-year old man with acute coronary syndrome (unstable angina petoris) was admitted to the coronary care unit. He had history of hypertension, diabetes mellitus and coronary artery bypass graft surgery. Physical examination was normal. He was treated with aspirin, [beta] blocker, clopidogrel, low molecular weight heparin, angiotensin converting enzyme inhibitor and intavenous nitroglycerin. Electrocardiographic and cardiac enzyme changes were not observed during the three days of follow-up. Coronary angiography showed a patent left internal mammarian artery to the left anterior descending artery with critical stenoses in the proximal and the mid segments, a patent saphenous vein graft (SVG) to the first diagonal branch with 70% stenosis and 80% thrombotic lesion in SVG to the obtuse marginal branch (Fig. 1, left panel, Video 1. See corresponding video/ movie images at www.anakarder.com). Percutaneous coronary intervention (PCI) was planned for SVG lesion. Followed by glycoprotein IIb/IIIa inhibitor (tirofiban) 25 pg/kg/3min loading dose, a 24-hour continuous 0.15 pg/kg/min infusion were given and then the patient underwent coronary intervention. We found that the SVG lesion disappeared (Fig. 1, right panel, Video 2. See corresponding video/movie images at www.anakarder.com). In conclusion, in thrombotic saphenous vein graft lesions when PCI is planned, if emergency is not necessary, administration of glycoprotein Ilb/Illa may obviate the need for any intervention.

[FIGURE 1 OMITTED]

Abdi Bozkurt, Abdurrahman Tasal, Esmeray Acarturk,

Department of Cardiology, School of Medicine,

Cukurova University, 01330, Adana, Turkey

Address of Correspondence/Yazisma Adresi: Abdi Bozkurt, MD, Cukurova University, School of Medicine, Department of Cardiology, 01330, Adana, Turkey Phone/Fax: +90 322 338 71 35 E-mail: abozkurt@cu.edu.tr
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Title Annotation:E-page Original Images/E-sayfa Orijinal Goruntuler
Author:Bozkurt, Abdi; Tasal, Abdurrahman; Acarturk, Esmeray
Publication:The Anatolian Journal of Cardiology (Anadolu Kardiyoloji Dergisi)
Article Type:Brief article
Geographic Code:7TURK
Date:Apr 1, 2008
Words:275
Previous Article:The accordion phenomenon/Akordiyon fenomeni.
Next Article:The imaging of the aortic fibrous membrane associated with Williams syndrome/Williams sendromu ile iliskili aortik fibroz membran goruntusu.
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