Therapeutic Management of Acute Pharyngitis in a Pup.
A four month old Chippiparai male puppy was brought with history of recurrent retching, coughing and unilateral discharge from nostril since one week. Clinical examination revealed pharyngitis, bilateral enlargement of submandibular lymphnodes and pyrexia. Cultural examination revealed presence of Streptococcal sp. and was highly sensitive to Cefpodoxime. The animal was treated with oral Cefpodoxime for five days and recovered eneventfully.
Keywords: Cefpodoxime; pharyngitis; submandibular lymphnode
Respiratory disease inducing pharyngitis in canines is multifactorial and a number of viral and bacterial pathogens have been reported as potential aetiological agents, including canine parainfluenza virus, canine adenovirus and Bordetella bronchiseptica, as well as mycoplasmas, Streptococcus zooepidemicus, canine herpesvirus and reovirus -1,-2 and -3 (Buonavoglia et al., 2007). All these respiratory pathogens are transmitted by direct contact with respiratory secretions of infected dogs. Environmental factors and host immune response play equally important roles in development of respiratory disease in canines (Cruickshank et a/.,1975).
History and Observation
A four month old, vaccinated Chippiparai male puppy weighing 6.6 kg was brought with history of recurrent retching, coughing and unilateral discharge from nostril since a week. Clinical examination revealed pain on palpation of pharyngeal region, bilateral enlargement of submandibular lymphnodes, congested mucous membrane and pyrexia (103.4[degrees]F). Animal showed coughing and retching behavior on palpation of pharyngeal region and gagging reflex was present.
Animal was subjected to Xray to rule out presence of foreign body. Further to indentify the etiology, a sterile swab was collected from purulent material aseptically. As per standard microbiological procedures, pure culture isolation was done as per Cruickshank et al. (1975).
Antibiogram was done as per the guidelines of National Committee for Clinical Laboratory Standards (NCCLS). The following antibiotics are used for resistance test: Amikacin, Amoxyclav, Ampicillin, Cefpodoxime, Cefixime, Cefpodoxime, Ceftriaxone, Gentamicin, Azithromycin, Erythromycin, Streptomycin and Chloramphenicol.
Treatment and Discussion
Animal being a young one, it is immunologically weak and environment on that particular week was hot and humid with occasional showers of rain which was the predisposing factor that facilitated infection. Further no foreign body could be detected in X-ray, which narrowed down to the etiology of microbial origin. Bacterial isolates of purulent discharge revealed presence of Streptococcus sp. The results of ABST revealed that the isolates were sensitive for Cefpodoxime. Similar results were obtained by Appelbaum et al. (1989).
The animal was given Tab. Cefpodoxime (Cefpet (a)) @ 10 mg/kg for 5 days SID. Animal showed complete recovery on fifth day with no purulent discharge from nose and other signs like retching and cough were completely ceased on fifth day. Similar results were obtained in humans (Portier et al., 1990).
It is concluded that use of Cefpodoxime is found effective against pharyngitis of streptococcal etiology in canines.
Appelbaum, P.C., Spangler, S.K., Crotty, E. and Jacobs M.R. (1989). Susceptibility of penicillin-sensitive and -resistant strains of Streptococcus pneumoniae to new antimicrobial agents, including daptomycin, teicoplanin, cefpodoxime and quinolones. J. Antimicrob. Chemother. 23: 509-16.
Buonavoglia, C. and Martella, V. (2007). Canine respiratory viruses. Vet. Res. 38: 355-73.
Cruickshank, R., Duguid, J.P., Marmion, B.P. and Swain, R.H.A. (1975). Medical Microbiology Vol. II, 12th edn, Crurchill Living Stone, New York, p. 31-57 and 96-218.
Portier, H., Chavanet. P., Gouyon, J.B. and Guetat, F. (1990). Five day treatment of pharyngotonsillitis with cefpodoxime proxetil. J Antimicrob Chemother. 26: 79-85.
K. Mohanambal (1), P.A. Enbavelan (2) and R. Ramprabhu (3)
Department of Veterinary Medicine Veterinary College and Research Institute Tamilnadu Veterinary and Animal Sciences University (TANUVAS) Tirunelveli--627358 (Tamil Nadu)
(1.) Assistant Professor and Corresponding author. E-mail: firstname.lastname@example.org
(2.) Assistant Professor
(3.) Professor and Head
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|Title Annotation:||Short Communication|
|Author:||Mohanambal, K.; Enbavelan, P.A.; Ramprabhu, R.|
|Article Type:||Clinical report|
|Date:||Jul 1, 2016|
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