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The ubiquitin proteasome system in the central nervous system; from physiology to pathology; 2008 update.

9781607416944

The ubiquitin proteasome system in the central nervous system; from physiology to pathology; 2008 update.

Ed. by Mario Di Napoli and Cezary Wojcik.

Nova Science Publishers

2010

552 pages

$129.00

Hardcover

Biochemistry research trends series

QP552

Nearly seven percent of all genes encoded by the human genome comprise elements of the ubiquitin-proteasome system, making it the most complex of all biochemical pathways. Here researchers in a wide range of biological and medical sciences review the scientific literature published through 2008 on 24 aspects of the system. The topics include mechanism and substrate specificity, the role and function of the system in neural stem and progenitor cells, the interrelationship between reactive oxygen species and proteasome inhibition as inducers of neuronal cell death, the validity of targeting the ubiquitin proteasome system in establishing new animal models of Parkinson's Disease, and tuning nodal signaling through the ubiquitin-proteasome system.

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Publication:Reference & Research Book News
Article Type:Book review
Date:Feb 1, 2011
Words:154
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