The three-pronged attack of depression triggers.
People who have low self-esteem, or who are readily overwhelmed by stress, are prone to depression.
Whether this a psychological predisposition or an early form of the illness is not clear.
Medical illnesses such as a heart attack, cancer, Parkinson's disease, and hormonal disorders can lead to depressive illness. Also, a serious loss, difficult relationship, financial problem, or any stressful change in life patterns can trigger a depressive episode.
Often, a combination of genetic, psychological, and environmental factors is involved in the onset of a depressive disorder.