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The cannabinoid receptors.


The cannabinoid receptors.

Ed. by Patricia H. Reggio.

Humana Press Inc.


396 pages



The receptors


There are two kinds--CB1 and CB2--and especially the first is now known to mediate the short-term and long-term retrograde inhibition of synaptic transmission, and to play a role in mediating the psychoactive principle in cannabis, learning and memory, analgesia, appetite regulation, and neuroprotection. Biochemists and other scientists synthesize the current understanding of such aspects as structure-activity relationships and conformational freedom of CB1 receptor antagonists and inverse agonists, cannabinoid receptor signal transduction pathways, mutational analyses of the receptors, new insights into the endo-cannabinoid system using knockout mice, and therapeutic applications for agents that act at CB1 and CB2 receptors.

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Publication:SciTech Book News
Article Type:Brief article
Date:Jun 1, 2009
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