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The biology of cancer, 2d ed.


The biology of cancer, 2d ed.

Weinberg, Robert A.

Garland Science


960 pages



In this text for undergraduate, graduate, and medical school students studying the molecular and cellular bases of cancer, Weinberg (cancer research, Massachusetts Institute of Technology) presents the principles of cancer biology. Chapters address topics such as the biology and genetics of cells and organisms; the nature of cancer; tumor viruses; cellular oncogenes; growth factors, receptors, and cancer; cytoplasmic signaling circuitry; tumor suppressor genes; control of the cell cycle clock; apoptosis; cell immortalization and tumorigenesis; maintenance of genomic integrity and the development of cancer; heterotypic interactions and the biology of angiogenesis; tumor immunology and immunotherapy; and recently developed therapies. This edition has been revised and updated to include recent advances and information on the tumor microenvironment, metastatic dissemination, tumor immunology, cancer stem cells, the epithelial-mesenchymal transition, multi-step tumorigenesis, invasion and metastasis, mutation of cancer cell genomes, epigenetic contributions, microRNA involvement, and the Warburg effect, with more on traditional therapy and a new list of key techniques. Garland Science is an imprint of Taylor & Francis Group.

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Publication:Reference & Research Book News
Article Type:Brief article
Date:Aug 1, 2013
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