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The Dynamic Synapse: Molecular Methods in Ionotropic Receptor Biology.


The dynamic synapse; molecular methods in ionotropic receptor biology.

Ed. by Josef Kittler and Stephen Moss.

CRC / Taylor & Francis


317 pages



Frontiers in neuroscience


Writing for researchers interested in techniques, methods and conceptual advances used for studying neurotransmitter receptors and other synaptic proteins, the contributors of these 15 papers describe a broad array of molecular, biochemical, imaging, and electrophysiological approaches. Topics include AMPA receptor trafficking, long-term plasticity at inhibitory synapses, proteomics of the PSD, phosphorylation of site-specific antibodies, protein palmitoylation by the DHHC protein family, antibody labeling and biotinylation approaches to study neurotransmitter receptors, visualization of AMPAR trafficking and surface expression, neurotransmitter dynamics, receptors dynamics and functional tagging, RNAi and applications in neurobiology, transfecting and transducing neurons, expression of recombinant proteins in rat brains using Sindbus virus, Lentivirus-based genetic manipulation, AMPA receptor phosphorylation in synaptic plasticity, and genomic and post-genomic tools for studying synapse biology.

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Publication:SciTech Book News
Article Type:Book Review
Date:Sep 1, 2006
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