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The 9th spring seminar of the Korean pathologists association of North America.

This special section represents the compiled lectures on gastrointestinal, liver, and pancreatic tumors presented at the 9th Spring Seminar of the Korean Pathologists Association of North America (KOPANA) held on March 18 to 20, 2010, in Washington, District of Columbia, in conjunction with the 99th Annual Meeting of the United States and Canadian Academy of Pathology (USCAP). Topics covered include a review of the molecular aspects of colorectal and pancreatic cancers, as well as an update on precursor and early lesions of hepatocellular carcinoma.

In his article, Gyeong Hoon Kang, MD, addresses the following topics: (1) 4 molecular subtypes of colorectal cancer exist, which can be defined by the combination of CpG island methylator phenotype and microsatellite instability (MSI) status, with their own clinicopathologic features and precursor lesions; and (2) a geographic difference exists in MSI rate and BRAF mutation rate of colorectal cancers. In her article, Young Nyun Park, MD, PhD, addresses the morphologically recognizable lesions during hepatocarcinogenesis, which include dysplastic lesions (dysplastic foci and dysplastic nodule) and small cancerous lesions ([less than or equal to] 2 cm in diameter) (early hepatocellular carcinoma [HCC] and small progressed HCC). Their pathologic features are discussed with emerging biomarkers.

In the article by Seung-Mo Hong, MD, PhD, Jason Y. Park, MD, PhD, Ralph H. Hruban, MD, and Michael Goggins, MD, the authors review the genetic and epigenetic mechanisms of pancreatic cancer in the context of histologic features.

KOPANA was founded in 1992 and has a membership of more than 200 Korean pathologists in North America who are practicing in a variety of venues such as universities, community hospitals, private laboratories, or research institutes. Currently, about 50 American pathologists of Korean heritage (Korean-American pathologists) regularly attend annual USCAP meetings and have KOPANA membership. This number is growing every year.

Ten years ago KOPANA started the Spring Seminar in conjunction with the Annual Meeting of USCAP to provide networking, educational, and recreational opportunities for our members. Our Spring Seminar has been an excellent educational event with speakers selected from among Korean-American pathologists and pathologists practicing in Korea. This has become an ideal venue for professional networking between Korean-American pathologists and pathologists in Korea, particularly for pathologists-in-training (members of the Korean Society of Pathologists). Indeed, participation by young Korean pathologists continues to grow, both in our educational program and at the USCAP meeting.

On behalf of KOPANA, we would like to express our appreciation to the editorial board of Archives of Pathology & Laboratory Medicine for the invitation to publish our meeting's lectures in this forum. We hope this special section will be of great benefit to both pathologists in Korea and readers of the ARCHIVES.

Eun Y. Lee, MD, professor and the director of surgical pathology at University of Kentucky, Lexington, graduated from Kyung Hee Medical School, Seoul, Korea, in 1978. He received training in anatomic and clinical pathology at University of Medicine and Dentistry of New Jersey in Newark and completed fellowship training in gastrointestinal pathology at Washington University Medical School in St Louis, Missouri, under the direction of Dr Katherine DeSchryver. Dr Lee has more than 70 peer-reviewed publications predominantly in the field of gastrointestinal and liver pathology. He is currently on the editorial board of Human Pathology and has served as a reviewer for numerous other journals including Archives of Pathology & Laboratory Medicine. He has been serving as treasurer for 2 years and general secretary/treasurer of the Korean Pathologists Association of North America for the last 16 years.

Jae Y. Ro, MD, PhD, earned his medical and doctoral degrees from Yonsei University School of Medicine in South Korea in 1969 and 1973, respectively. After completing his residency in anatomic pathology at Yonsei University Severance Hospital in Korea, he received additional residency training in anatomic and clinical pathology at Case Western Reserve University Institute of Pathology in Cleveland, Ohio. He then completed his fellowship in surgical pathology in 1985 at The University of Texas M. D. Anderson Cancer Center at Houston and remained at the same institution as an assistant professor, becoming a full professor in 1992. He served as surgical pathology fellowship program director and codirector for 6 years from 1996 until 2001. From 1998 to 2005, he was the chairman and director of anatomic pathology at Ulsan University Asan Medical Center in Seoul, Korea. In 2005, Dr Ro moved back to Houston, Texas, and joined the Department of Pathology at The Methodist Hospital, where he is currently the director of surgical pathology and professor of pathology at Weill Medical School of Cornell University. Dr Ro is the recipient of the Educator of the Year, 2001, The University of Texas, M. D. Anderson Cancer Center, the recipient of 2007 Harlan J. Spjut Award from the Houston Society of Clinical Pathologists, and the recipient of Academic Achievement Award from Yonsei University, College of Medicine in 2010. He is a section editor and member of the executive advisory board for the Archives of Pathology & Laboratory Medicine. He is an editorial board member for Advances in Anatomic Pathology and The Korean Journal of Pathology and served as a reviewer for numerous other journals including Urology, Human Pathology, Modern Pathology, and The American Journal of Surgical Pathology. He has published more than 580 scientific articles, 4 books, and 40 book chapters. He has been serving as general secretary for 2 years, vice president for 2 years, president for 2 years, and an advisory member of the Korean Pathologists Association of North America for the last 18 years.

Eun Y. Lee, MD; Jae Y. Ro, MD, PhD

Accepted for publication September 23, 2010.

From the Department of Pathology and Laboratory Medicine, University of Kentucky, Lexington (Dr Lee); and the Department of Pathology, The Methodist Hospital, Weill Medical College of Cornell University, Houston, Texas (Dr Ro).

The authors have no relevant financial interest in the products or companies described in this article.

Reprints: Jae Y. Ro, MD, PhD, Department of Pathology, The Methodist Hospital and Weill Medical College of Cornell University, 6565 Fannin, M227, Houston, TX 77030 (e-mail:
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Author:Lee, Eun Y.; Ro, Jae Y.
Publication:Archives of Pathology & Laboratory Medicine
Date:Jun 1, 2011
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