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Byline: S.T.Y. Azeemi, S.F. Shaukat, R. Qasim, A. Azeemi and N. Saqib

ABSTRACT: The study objective was to conduct a randomized, placebo controlled clinical trial to assess the treatment option of recurrent urinary tract infections (RUTIs) by color therapy, an alternative treatment recently emerging with serious scientific background. Sixty pregnant female patients with the history of RUTIs were enrolled in Mansoorah Al-Khidmat Teaching Hospital, Lahore (Pakistan) between 17th October to 27th October, 2015. Chromotherapy was adopted as the method of treatment for RUTIs for one group (n=30), using the method of hydrochromotherapy. Green Chromotized water was given to the patients. The remaining patients (n=30) were given placebo treatment. At the end of three-week study, the patients free of UTI was significantly lower in chromotherapy group as compared to placebo (p10 5 CFU/ml. Only the cultures with bacterial growth >(10 5 CFU/ml) were recorded as events. Kaplan-Meier Analysis was carried out using SPSS Version 20 (Fig.1).


During the period of eight months, five (16.7%) women in the chromotherapy group and 18 (60%) in the placebo group had at least one episode of UTI, out of total 23 episodes of UTI. Cumulative proportion of the patients remaining free of urinary tract infection as clearly indicated by Kaplan Meier Analysis was significantly lower in the chromotherapy than in the placebo group (p<0.001 by Log-Rank test). 95% confidence interval for chromotherapy group is 7.0-8.0 and 4.5-6 for placebo. This is the clear indication of the successful prevention of urinary tract infections through visible range electromagnetic radiations.


Electromagnetic energy fields including microwaves, radio-frequencies, and the visible electromagnetic radiations, have been shown to greatly impact every characteristic of biological regulation. Cell division, DNA, RNA, protein synthesis and nerve conduction, are all affected by specific frequencies of electromagnetic radiation (Candace Pert and Oschman, 2000). There is sufficient evidence in the photo-biological literature on the effects of long wavelength ultraviolet and near visible range radiations on Escherichia Coli (Eisenstark, 1987; Hollaender, 1943). Visible light lasers acting as bactericidal agents have proven useful in removing bacterial biofilms (Nandakumar et al., 2006).

Recurrent UTIs are major therapeutic concerns especially in pregnancy where antibiotic resistance is a major problem. Not only is the increase in resistance of Gram-negative bacteria faster than in Gram-positive bacteria, but also there are fewer new and developmental antibiotics active against Gram-negative bacteria (Wise and Piddock, 2010). Several of alternative therapies have emerged for RUTIs including cranberry juice for UTI susceptible women (Burleigh et al., 2013; Hisano et al., 2012). However, Visible Range Radiation therapy / Color Therapy is recently emerging as a viable therapeutic technique in the field of energy/vibrational medicine (Benchea et al., 2015; Elkina et al., 2013; Gul et al., 2015), with important implications particularly in the regimen of bacteria borne diseases.

In our previous report, we investigated the in vitro effects of visible range radiations on E. coli (Azeemi et al., 2017) and the analysis of the SEM images of irradiated E. coli samples showed that the most profound inhibitory effects on E.coli amongst every applied radiation in the visible region were that of 538nm Visible Range Radiation (Green) which proved to be bactericidal.

Previously, a conjecture describing charged quantization phenomena in water samples that were chromotized, was also developed pertaining to hydrochromotherapy, which conjectured that quantum mechanical dipole moment of water molecules after the absorbance of different visible range electromagnetic radiations in the irradiated water samples may lead to the charge quantization phenomena. The water molecules which acquire vibrational energies produce a geometrical shape i.e., hectagon, pentagon, hexagon, and nanogon with molecules having same frequency of any visible color (resonant states) (Azeemi, S. Mohsin Raza, et al., 2008). These geometrical structures in chromotized water are responsible to influence the migration rate of the ions, salts, etc. within intra macromolecule cells. This may constitute as one of the primary reasons Hydrochromotherapy helps in getting a relief from various diseases (Azeemi, Raza, et al., 2008; Mayer and Bhikha, 2014).

One of the advantages of visible light is, that instead of mercury arc lamps, simple color filter sheets under bright sun / full spectrum light bulb could be used, which are commercially available and therefore cost-efficient concerning the visible light spectrum. Due to the simplicity of the whole procedure and the quick absorption of chromotized water, this method was adopted for pregnant patients. This is absolutely non-teratogenic, without any risk of adverse reactions or side-effects. As the results show, there was a persistent and clear difference in the occurrence of urinary tract infection between the Chromotherapy and placebo.

Conclusion: It was concluded that 538 nm radiations can be used for treating recurrent UTIs in pregnancy against resistant E.coli.


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Publication:Pakistan Journal of Science
Article Type:Clinical report
Date:Dec 31, 2017

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