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T-PA as stroke treatment?

Tissue plasminogen activator (t-PA), a clot-busting enzyme that is showing value in reducing damage after heart attacks (SN: 4/13/85, p. 229), may someday prove useful in stroke patients as well. Both strokes and heart attacks can occur when a clot lodges in a blood vessel, blocking blood flow. In the Dec. 13 SCIENCE researchers from the University of California's San Diego campus and University of Massachusetts in Worcester report the enzyme effectively protects rabbits from the neurological damage that occurs when a blood clot is induced in the brain; proper dosage information and proven efficacy with larger clots will be needed before the procedure can be tried on human patients, they say.
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Title Annotation:tissue plasminogen activator
Publication:Science News
Date:Dec 14, 1985
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