Commercially available calcium sulfate hemihydrate (CSH) powders
were mixed with anhydrous calcium hydrogen phosphate (monetite) in order
to develop a novel resorbable orthopedic cement. The setting solution,
distilled water, converted the CSH into gypsum as proven by an X-ray
diffraction. This conversion into gypsum is what gives the cement its
high compressive strength. The addition of monetite gives the cement a
high bioresorbablity and remodeling ability that is not present in the
pure, CSH cements on the market today. Instead of merely dissolving into
powder when placed in body fluids like CSH cements, the
phosphate-enhanced cement in vivo may convert into apatitic bone-like
structures.
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