Syngenta Participations AG (Basel, Switzerland) has patented the
Arabidopsis NI16 gene isolated in a yeast 2-hybrid screen via its
interaction with the NIM1 protein. The NI16 gene encodes a protein
involved in the regulation of SAR gene expression in plants. NI16 is
strongly induced in NIM1-overexpressing plants treated with
benzo(1,2,3)thiadiazole-7-carbothioic acid S-methyl ester. The NIMI interactor can be expressed in transgenic plants, either alone or in
combination with the NIMI protein, to increase expression of SAR genes
such as PR-1. (US 6,706,952)