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Survival with HAART.

A study from Denmark suggests that the death rates in people with HIV have fallen significantly since 1995--since the introduction of highly active antiretroviral therapy (HAART). The latest figures suggest that a 25-year-old with HIV can now expect to survive for more than 35 years, although concurrent infection with hepatitis C reduces this survival to around 32 years.

These estimates are obtained from a cohort of all Danish adults with HIV--but do depend on HAART continuing to work well through life. The authors say that they have found no evidence of HAART becoming less effective with time, despite potential problems with multidrug resistance and serious side-effects. This means that the prognosis for those with HIV--in the developed world--approaches that associated with type 1 diabetes. However, even in Denmark, the outlook for those living with HIV remains far worse than the outlook for healthy people. In this study the current mortality rates for young adults with HIV were 9-15 times higher than the rates for age-matched adults without HIV.

Lohse N, et al. Ann Intern Med 2007; 146: 87-95.
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Title Annotation:single suture; highly active antiretroviral therapy
Author:Lohse, N.
Publication:CME: Your SA Journal of CPD
Article Type:Brief article
Geographic Code:4EUDE
Date:Mar 1, 2007
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