Printer Friendly

Study details new molecular approach to preventing Alzheimer's.

Study details new molecular approach to preventing Alzheimer's.

The April 24 Washington Post reported that German researchers have developed a new approach to the possible prevention of the molecular "debris" that is associated with the development of Alzheimer's disease. The basic idea--to block the activity of an enzyme called beta secretase--is not original, says a new study's lead author. Both academic and commercial laboratories are working on methods to prevent the enzyme from slicing a protein into beta-amyloid fragments that form the brain plaques found in victims of the disease. Most experts now agree that formation of the beta-amyloid plaques is directly linked to the development of Alzheimer's. The problem with most proposed methods of blocking beta secretase, the study found, is that they are designed to work outside of the affected brain cells. The researchers point out that the process of cleaving takes place inside cells, so they have constructed an inhibitor, which binds outside, on the cell membrane, and goes into the cell where the cleavage occurs.
COPYRIGHT 2008 Nelson Publishing
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2008 Gale, Cengage Learning. All rights reserved.

Article Details
Printer friendly Cite/link Email Feedback
Title Annotation:New studies
Publication:Medical Laboratory Observer
Article Type:Brief article
Geographic Code:4EUGE
Date:Jun 1, 2008
Previous Article:American retailers to phase out BPA-tainted baby bottles.
Next Article:Conferences.

Related Articles
Debate over Alzheimer's enzyme flares up.
Psychology of Aging in the 21st Century.
Old antibiotic takes on Alzheimer's.
Statins take on the brain; cholesterol-lowering drugs may also fight Alzheimer"s disease.
Alzheimer's vaccine trial is suspended. (Biomedicine).
Alzheimer's disease vaccine abandoned. (Biomedicine).
Delaying dementia: drugs that fail as cures might still prevent Alzheimer's disease.
Natural substance prevents and stops Alzheimer's disease.
Ask Dr. Nan.
Take a walk: prevent Alzheimer's disease.

Terms of use | Privacy policy | Copyright © 2020 Farlex, Inc. | Feedback | For webmasters