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Strep's role in acute otitis media.

AOM caused by Streptococcus pyogenes was associated with older age and higher rates of tympanic perforation and mastoiditis, compared with AOM caused by other pathogens, said Nili Segal, M.D., and associates at Ben-Gurion University of the Negev, Beer-Sheva, Israel (Clin. Infect. Dis. 2005;41:35-41). In the study of 11,311 episodes, overall, those caused by S. pyogenes, also known as group A [beta]-hemolytic Streptococcus (GAS), were significantly less Often associated with fever or upper respiratory tract infection, compared with non-GAS episodes (60% vs. 77% and 35% vs. 55%, respectively). GAS episodes also were significantly less likely to be bilateral, or to be associated with antibiotic treatment during the month prior to the infection. The increased risk of mastoiditis supports data from previous studies, Stanford T. Shulman, M.D., and Robert R. Tanz, M.D., of Northwestern University, Chicago, wrote in an accompanying editorial (Clin. Infect. Dis. 2005;41:42-4). Episodes of GAS otitis media may be preceded by pharyngeal colonization; this colonization may contribute to the increased frequency of mastoiditis in these patients.

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Title Annotation:Clinical Capsules
Author:Splete, Heidi
Publication:Family Practice News
Article Type:Brief Article
Geographic Code:7ISRA
Date:Aug 15, 2005
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