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Stalking a vaccine for skin cancer.

Stalking a vaccine for skin cancer

Taking some of the hair of the dog that bit you mab prove sound advice when it comes to skin cancer.

David Berd, an oncologist at Thomas Jefferson University in Philadelphia, injected 24 patients who had metastatic melanoma with pieces of their own tumors coated with the immune-system sensitizing agent dinitrophenyl. This month, at the First International Symposium on Combination Therapies in Washington, D.C., he reported that 14 of the volunteers developed an increased immune response to their cancers.

In an earlier study using uncoated tumor cells, Berd found that five of 40 patients showed significant tumor regression. Despite melanoma's extremely high mortality, one patient is still alive eight years after diagnosis, he says. These studies "provide some basis for optimism" about the prospect of developing a vaccine to boost immune responses to melanoma and possibly other cancers, he conludes.
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Title Annotation:metastatic melanoma
Publication:Science News
Date:Mar 30, 1991
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