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Shivering mice 'warmed' by gene therapy.

Shivering mice "warmed' by gene therapy

Injection of a normal gene that codes for a nerve-cell-sheathingprotein can cure a type of mouse suffering from tremors and convulsions, say the authors of two reports in the Feb. 27 CELL. Mice carrying the "shiverer' gene mutation, which can lead to early death, do not produce myelin basic protein (MBP), essential for the conduction of nerve messages. The therapeutic genes were injected into fertilized shiverer eggs, which developed into individuals free of the abnormal behavior caused by lack of MBP. The research was done at Pasadena's California Institute of Technology and at Harvard Medical School in Boston.
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Publication:Science News
Date:Mar 21, 1987
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