Printer Friendly

Selective Genetics obtains United States patent.

Selective Genetics, Inc. has patented preparations of conjugates of a receptor-binding internalized ligand and a cytocide-encoding agent and compositions containing such preparations. The conjugates contain a polypeptide that is reactive with an FGF receptor, such as bFGF, or another heparin-binding growth factor, cytokine, or growth factor coupled to a nucleic acid binding domain. One or more linkers may be used in the conjugation. The linker is selected to increase the specificity, toxicity, solubility, serum stability, or intracellular availability, and promote nucleic acid condensation of the targeted moiety. The conjugates are complexed with a cytocide-encoding agent, such as DNA encoding saporin. Conjugates of a receptor-binding internalized ligand to a nucleic acid molecule are also provided. (US 6037329)
COPYRIGHT 2000 Biotech Patent News
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2000 Gale, Cengage Learning. All rights reserved.

Article Details
Printer friendly Cite/link Email Feedback
Title Annotation:Selective Genetics Inc.
Comment:Selective Genetics obtains United States patent.(Selective Genetics Inc.)
Publication:BIOTECH Patent News
Article Type:Brief Article
Geographic Code:1USA
Date:Nov 1, 2000
Words:116
Previous Article:Myriad obtains United States patent.
Next Article:Amgen obtains United States patent.
Topics:


Related Articles
Targeted Genetics licenses key gene expression technology to GTI/Systemix.
Myriad Genetics awarded United States patent on P16 cancer protein and antibodies to protein.
Myriad Genetics awarded cancer gene patents.
Paradigm Genetics receives herbicide target patent.
Targeted Genetics obtains gene expression patent.
Targeted Genetics' obtains adeno-associated virus patent.
Lexicon patents gene trapping technology.
Lexicon extends intellectual property portfolio with patent on gene trapping.

Terms of use | Privacy policy | Copyright © 2019 Farlex, Inc. | Feedback | For webmasters