See-and-touch 3-D molecule.
Seeing may aid believing, but feeling aids understanding, especially when it comes to modeling complex molecules like this binding pocket of a mutant antibody. Michael Pique and Jim Emery of the Scripps Research Institute in La Jolla, Calif., converted X-ray data about the antibody's structure into a set of coordinates. Then Allied-Signal Aerospace Co. in Kansas City, Mo., used stereolithography (SN: 8/3/91, p.72) to build this true-to-life, copyrighted model. In the eight-hour-long 3-D printing process, a precisely aimed laser solidifies liquid plastic at specified coordinates. "It's an easy way to develop a physical intuition of what a molecule is like," says Sylvia J. Spengler, a biophysicist at the University of California, Berkeley.
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|Title Annotation:||complex molecule models give structure to research|
|Article Type:||Brief Article|
|Date:||Nov 21, 1992|
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