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Scientists' 3D tech to scan cancer cells.

CARDIFF University researchers have developed a groundbreaking new microscope which allows them to examine cancer cells in 3D.

Professors Trevor Dale and Paola Borri claim the pioneering technology could lead to the discovery of new cancer treatments.

They were given a grant of nearly PS480,000 by Cancer Research UK and Channel 4's Stand Up To Cancer campaign to fund their three-year research project.

Prof Dale said: "Most research examines cancer cells in 2D in the lab, where they grow flattened out on plastic dishes.

"Our research is more advanced as we are using technology that allows us to grow cancer cells as 3D miniature tumours called organoids.

"These organoid structures more closely resemble a living tumour in a person and can help us better understand different people's cancers and how drugs can be used to treat them."

Profs Dale and Borri say it can be difficult to study organoids because not all microscopes are equipped to visualise these complex 3D structures. But they say their microscope is able to manage it.

Using a technique called CARS (Coherent Anti-Stokes Raman Scattering) and laser beams the pair can monitor the vibrations of molecules inside the cancer organoids to see how new treatments affect - or kill - them.

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Publication:South Wales Echo (Cardiff, Wales)
Date:Oct 19, 2017
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