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Schizophrenia: gender connections.

Schizophrenia: Gender connections

There are preliminary indications that the corpus callosum-- a bundle of nerve fibers connecting the right and left brain hemispheres -- displays gender-specific abnormalities among schizophrenics, according to a report at the annual meeting of the American College of Neuropsychopharmacology held last week in Washington, D.C.

Significantly fewer fibers connecting the frontal lobes, comparedwith fibers connecting the occipital lobes, were found among 24 right-handed schizophrenic males, while the reverse was observed among 10 right-handed schizophrenic women. In a group of 41 healthy volunteers, the same comparison revealed more frontal lobe fibers among males and more occipital lobe fibers among females, according to Henry A. Nasrallah of Ohio State University in Columbus and his colleagues.

The data, which are based on magnetic resonance images ofeach subject's corpus callosum, suggest that communication between the frontal lobes and overall frontal lobe functioning may be decreased among schizophrenic males, say the researchers; conversely, frontal lobe communication and activity may be abnormally elevated among schizophrenic females. The investigators note that other brain imaging techniques, such as those measuring cerebral blood flow and glucose metabolism, should be used to clarify gender differences in schizophrenics' brains.
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Publication:Science News
Date:Dec 20, 1986
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