Sad end for Rewilding.
The horse was on course to challenge for the race lead in the straight, but slipped throwing jockey Frankie Dettori to the ground in the process. The Italian injured his knee in the incident, but should be back in action for Glorious Goodwood next week.
Simon Crisford, Goldolpin racing manager, said: "It is a tragedy. Unfortunately, we have lost him as he has had to be put down."
"Rewilding, Godolphin's top older horse this year, was humanely put down after breaking his near fore leg," said Godolphin in a statement on its website.
It comes as a huge blow to the Dubai-based racing group, especially as Rewilding had scored a victory at the same course just a month earlier in the prestigious Prince of Wales's Stakes at Royal Ascot.
In March the horse had broken through at elite level with a runaway victory in the Dubai Sheema Classic at Meydan.
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