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SCIENTISTS IN DEMENTIA PROJECT.

LIVERPOOL scientists are playing a key role in a project that is using complex sugars to treat Alzheimer's disease.

The team, made up of experts from the University of Liverpool and Callaghan Innovation, in New Zealand, have developed a method which uses sugars, called heparan sulphates, to block the production of proteins in the brain that cause the progressive memory loss characteristic of Alzheimer's disease.

Professor Jerry Turnbull, from the university's Institute of Integrative Biology, said: "We are targeting an enzyme, called BACE, which is responsible for creating the amyloid protein.

"The amyloid builds up in the brain in Alzheimer's disease and causes damage.

"BACE has proved to be a difficult enzyme to block, despite lots of efforts by drug companies.

"We are using a new approach."
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Publication:Liverpool Echo (Liverpool, England)
Date:Jun 3, 2013
Words:127
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