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SAPHIR: Strengthening Animal Production and Health through the Immune Response.

Duration: From 2015-03-01 to 2019-02-28, ongoing project

Total cost: EUR 10 519 483,75

EU contribution: EUR 8 999 996,25

Objective: SAPHIR aims to develop vaccine strategies effective against endemic pathogens responsible for high economic losses in livestock in order to strengthen the profitability of food animal systems, improve animal welfare and reduce xenobiotic usage in farming with a One Health perspective.

SAPHIR will bring novel vaccine strategies to the market i) at short term, with several promising vaccines brought to demonstration (RTL6), ii) at long term, with cutting edge strategies brought at proof of concept (RTL3) and iii) in line with socio-economic requirements. SAPHIR has selected two representative pathogens of pigs (Porcine Reproductive and Respiratory Syndrome Virus and Mycoplasma hyopneumoniae), chickens (Eimeria and Clostridium perfringens) and cattle (Bovine Respiratory Syncytial Virus, Mycoplasma bovis) to develop generic vaccine approaches applicable to other pathogens.

SAPHIR will issue i) knowledge of immune mechanisms of protection, ii) affordable, safe and multivalent vaccines with DIVA properties, iii) efficient adjuvants targeting dendritic cells, optimal formulations, new mucosal and skin delivery systems, a new generation of DNA vectors and viral replicon platforms for fostering an earlier and longer duration of immunity including the perinatal period, and iv) basal biomarkers of individual immuno-competence for future breeding strategies. The SAPHIR dissemination and training programme includes creation of an integrated health management website, launch of a Global Alliance for Veterinary Vaccines and organization of workshops directed at food animal system stakeholders. This will ensure optimal research translation of SAPHIR outputs to market and field applications.SAPHIR brings together interdisciplinary expertise from fourteen academic institutes including a Chinese partner, five SMEs and two pharmaceutical companies.

Participants:

CARDIFF UNIVERSITY

United KingdomEU contribution: EUR 379 193,75

NEWPORT ROAD 30-36

CF24 ODE CARDIFF

United Kingdom

EIDGENOESSISCHES DEPARTEMENT DES INNERN

SwitzerlandEU contribution: EUR 0

Inselgasse 1

3003 BERN

Switzerland

EUROPEAN FORUM OF FARM ANIMAL BREEDERS

NetherlandsEU contribution: EUR 176 793,75

DREIJENLAAN 2K 1060 1061

6703 HA WAGENINGEN

Netherlands

INMUNOLOGIA Y GENETICA APLICADA SA

SpainEU contribution: EUR 445 193,75

Hermanos Garcia Noblejas 41

28037 MADRID

Spain

INRA TRANSFERT S.A.

FranceEU contribution: EUR 410 176,25

RUE DU DOCTEUR FINLAY 28

75015 PARIS

France

PARCO TECNOLOGICO PADANO S.R.L.

ItalyEU contribution: EUR 500 193,75

Via Einstein - Localita Cascina Codazza

26900 LODI

Italy

Shanghai Veterinary Research Institute - Chinese Academy of Agricultural Sciences

ChinaEU contribution: EUR 0

Z

Project completion date : 2019-02-28 12:00:00

Major organization : INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE

Address : 147 rue de l'Universit 75338

Paris Cedex 07

Country :France

Url : http://www.inra.fr

Financier : EUROPEAN UNION (EU),

Financier address : European Union (EU)

Rue de la Loi 200/Wetstraat 200,

B-1049 Bruxelles/Brussels,

Belgium

Tel: 32-2-2999696, 2993085

Fax: 32-2-2961749

Url: ec.europa.eu/

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Publication:Mena Report
Date:Jul 29, 2016
Words:470
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