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Rtl implementation of preprocessing stage for Ecg signals.


With rapid development of various technologies, more and more data are generated and transmitted in the medical, also the internet allows for wide distribution of digital media data. ECG is such a data used for diagnosing the heart diseases. The ECG sensor is dedicated to measuring the rate and regularity of heartbeats as well as the size and the position of the chambers. The overall magnitude of the heart's electrical potential is then measured from twelve different angles ("leads") and is recorded over a period of time (usually 10 seconds). In this way, the overall magnitude and direction of the heart's electrical depolarization is captured at each moment throughout the cardiac cycle. The graph of voltage versus time produced by this noninvasive medical procedure is referred to as an ECG. The ECG signals have 5 waves namely, P, Q, R, S and T waves. These five waves are shown in Fig. 1. In which the most important one is Q, R, S wave and is simply called as QRS complex.

The ECG signal analysis consists of three stages: Pre-processing stage - for providing clean ECG, Feature Extraction stage for the recognition of ECG signal characteristics and Decision stage for final diagnosis with the support of medical expert. For analyzing ECG, the QRS is the most important segment. The electrical interpretation of the cardiac muscle activity, it is very easy to interface with different noises while gathering and recording. The artifacts or noise sources are the instability of electrode skin effect, the power line interface and the base line wandering. The base line wandering is a low frequency component due to patient inhalation and exhalation. Thus the QRS complex overlaps with the muscle noise, P and T overlap with the respiration action [3]. Wavelet transformation denoising method deals with wavelet coefficient using a suitable chosen threshold value in advance.


Materials And Methodology:

The ECG signals required for this research is accessed from MIT/BIH database. Fig. 2 demonstrates the fundamental outline of the preprocessing phase of the ECG signal examination. We read annotation records for arrhythmia or QRS complexes by using MATLAB and we stack the database picture it simulates the plotted estimations of the diagram from that we can make the text document which is stacked in the VHDL code in Xilinx. At in the first stage, the ECG signal is given to the multilevel DWT to suppress the BLW and it experiences dilation, erosion and adaptive threshold process for the recognition of QRS. This the QRS is distinguished from the given signal.


A. Multilevel Design of DWT:

Two dimensional (2D) DWT has advanced as fundamental part of the modern compression system, for example, JPEG. Moreover, a wavelet based compression system presents superior compression performance, as well as gives four measurements of scalability resolution, distortion, spatial and color, which are extremely hard to accomplish in Discrete Cosine Transformation (DCT) based compression system. In a compression system, the function of DWT is to decorrelate the original image pixels prior to compression step such that they can be enable the compression. Therefore, many famous coders have been proposed to effectively compress images or frames processed via DWT. The calculation of DWT should be possible either by convolution based plan or lifting based plan. The lifting plan of calculation of DWT has, turn out to be more popular over the convolution based plan for its lower computational complexity [7].

The fundamental element of the lifting based DWT plan is to separate the high pass and low pass channels into an arrangement of upper and lower triangular matrices and change the filter implementation into banded matrix multiplications. Such a plan has a few advantages, including "in place" calculation of DWT, integer to integer WT, symmetric forward and reverse transformation. The ubiquity of lifting based DWT has set off the advancement of a few architectures [6].

The architecture lifting based 2D DWT developed has regular data flow and low control complexity, and achieves 100% hardware utilization. The fig. 3 demonstrates the 2D DWT. The other structural planning depended on the propriety of perfect reconstruction of filter bank developed in.


In the proposed construction modeling can be reconfigured for 5/3 and 9/7 WT [3] [4]. This lessens altogether the required quantities of the multipliers, adders, and registers as well as the amount of accessing external memory and prompts diminish productively the equipment cost and power consumption. In the architecture for one dimensional (1D) DWT standard can be stretched out to architectures for distinguishable 2D DWT like the one created. The Fig. 4 demonstrates the second level decomposition of 2D DWT.


B. QRS Detection:

The principle point is to change the digital images into various forms. Image processing methods are utilized with wide varieties of applications. The necessity is diverse for various applications. The QRS discovery is fundamentally focused around how to change the image utilizing mathematical morphology [1] [5], with the goal that it can be suitable for the separate applications. Mathematical morphology has been clarified how images are utilized to show a mathematical set of theoretical operations, such as union and intersection. This by method for morphological operations such as filtering, dilation and erosion. There are various applications utilizing diverse binary morphological operations e.g: object recognition, tracking and region filling. The current binary morphology utilizes the image processing with MATLAB simulation. The synthesis could be done with the FPGA architecture morphological operations include dilation and erosion and is similar to convolution [1]. Erosion can be used for shrinking the shapes and removing the bridged, branches and small protrusions. Dilation can be used for expanding the shapes and filling the holes, gaps and gulfs.

C. BLW Removal:

The BLW is a noteworthy sort of noise influencing an ECG, indeed its frequency range is as a rule underneath 0.8Hz and thus, overlaps with the ECG spectrum. There is an assortment of methodologies for BLW concealment or diminishment; among these routines, the most utilized are the high pass filtering and cubic line interpolation. As a promising system, the multilevel DWT connected to the BLW removal can give a great result this delays depend upon the time response of decomposition and reconstruction processes. At every level, the decomposition is described by a low pass filter and high pass filter operators [2]. We can go up to any level until we get certain aspect of the signal such as discontinuities or shifts etc. The multilevel decomposition gives the methods for best compression of data.

Internal Diagram:

The proposed morphology operator filtering assumes the most critical part in the proposed calculation which removes the noise and baseline drift and suppresses the P/T waves in ECG signal. The Fig. 5 demonstrates the inner outline in which multipixel modulus accumulation is utilized to enhance the QRS complex [1]. At last, the threshold is applied to choose the heart rate. The dilation extends an image object and erosion shrinks it.


The opening smoothes a contour in an image, breaking narrow isthmuses and taking out thin projections. Closing tends to narrow, smooth segments of contours, fusing narrow breaks and long thin gulfs, taking out little openings, and filling gaps in contours. In many applications, opening is utilized to smother peak while shutting is utilized to suppress pits [1][2]. Here, with a specific end goal to recognize QRS complex precisely and rapidly, a peak extractor is defined just taking into account fundamental dilation and erosion morphological administrators are given in equation (1) and (2), rather than a progression of cutting edge openings and closings.

h(n)=1/2 [f[phi] g(n) + f[phi] g(n)] (1)

v(n) = f(n) - h(n) (2)

The QRS complex will be improved and others waves that change easily will be mapped in horizontal axis after the cancelation of DC components. The signal data of interest, can be fundamentally controlled by three basic parameters of the structure component in the morphological filter. The shape (or slope) of the structure component is the most noteworthy variable, in this the littler slant performs better in terms of removing noise, but with a larger reduction in the amplitude of resulted signal. The less significant thing is the length of the structure component (i.e., the accepted span of the QRS complex), which differs with the patient and position of the electrode, and more structure component ends up leading to somewhat better execution as far as noise lessening, yet with a little decrease in amplitude of the QRS complex. The least significant item is the amplitude of the structure item. This filter the performance to a least sensitive level. The total estimation of the above yield is then consolidated by multiple frame accumulation, which is much similar energy transformation. The energy accumulation procedure is communicated in equation (3).

s(n)=[[summation].sup.+2] - [absolute value of ()] = [-.sub.2] - (3)

An adaptive threshold is used as the decision function as a part of association with the proposed transformation for QRS detection. Generally, the threshold levels are computed signal dependent such that an adaptation to changing signal characteristics is possible. It is suggested that, the required adaptive threshold is a function of the maximum of the transformed ECG waveform s(n). The rule in selecting the threshold T, is given by equation (4).

.1 max,< 3 T = {.3 , max 3 [less than or equal to][less than or equal to] 7 .13 ,< 7 (4)

Where max is determined from the present signal fragment which is within the range of millivolts. The upper and lower bounds of max will be liable for the selection of structural elements. The proposed VLSI design comprises of shift registers, ROM, adder, comparator and Finite State Machine (FSM) based controller. For the convenience of demonstration, the circuit realization of pivotal modules of a five point length structure element g(k), k= 1, 2, 3, 4 and 5.

The Register implies the shift registers, storing the intermediate values, and max/min represents the comparators for dilation and erosion. The components for the adder, i.e., Gmax/Gmin mean the difference between two values in the structure element, which are stored in the ROM. This can be computed by using equation (5) and (6).

Gmax(i) = g(i+1) - g(1) (5)

Gmin (i) = g(5) - g(5-i) (6)

This hardware design strategy aims to diminish the number of adders for dilation and erosion calculation, since it is equivalent to comparing the resulting items straightforwardly from the dilation and erosion regardless of the fact that one consistent number is included or subtracted before maximal and minimum comparisons. In this style, just four adders are required, rather than five, bringing about 20% savings for single channel. Under the current design, the computational core needs five sub clock periods to complete one calculation cycle: the first is to read five information from the registers for adder, followed by the clock period needed for the addition.

Experimenal Result:

The MIT/BIH arrhythmia database is utilized for the assessment of the proposed QRS detection algorithm. Figure 6 is the detection illustration performed from an MIT/BIH database of ECG signals.

The genuine ECG signal and its QRS recognition are acquired utilizing Model Sim software. The ECG signal varies from patients to patients. For checking this calculation, different ECG signals are utilized. The waveform of various patients and yields are demonstrated as follows.


Figure 7 demonstrates the filter outputs, LL, LH, HH and HL used to suppress the BLW. Figure 8, 10 and 12 are the ECG signals acquired from an MIT/BIH database and Figure 9, 11, 13 are the corresponding outputs.









The ECG sensor is committed to measuring the rate and consistency of heart beats and also the size and position of the chambers. In multilevel DWT it experiences more separating stage than DWT. The implementation of the algorithm was tried effectively utilizing VHDL language. The BLW is smothered utilizing multilevel DWT and the QRS is distinguished utilizing dilation, erosion and modulus accumulation. The ECG signal fluctuates from patients to patients. For checking this calculation, the different ECG signals are utilized. In our present world ECG is utilized to distinguish heart issues up to a specific level. The proposed framework can do the evacuation of noise and identification of QRS. This framework acknowledges ECG from an information base known as MIT/BIH and it can't compute ECG straightforwardly. In the future, we can broaden the framework as measuring ECG specifically from people. Thus, provides a better diagnosis of patient difficulties.


[1.] Chris, F. Zhang and Tae- Wuk Bae, 2012. "VLSI friendly ECG QRS complex detector for body sensor networks" IEEE journal on emerging and selected topics in circuit and systems, 2(1): 52-59.

[2.] Dora, M., 2012. Ballesteros, Diana Marcela Moreno, Andres E. Gaona, "FPGA compression of ECG signals by using modifid convolution scheme of the discrete wavelet transform," Ingeniare revista chilena de ingenieria, 20(1): 28-16.

[3.] EL Mimouni EI Hassan, Mohammed Karim, 2014. "An FPGA based implementation of a pre-processing stage for ECG signal analysis using DWT", Browse conference publications, Complex systems (WCCS), pp: 649-654.

[4.] Mikhled Alfaouri, Khaled Daqrouq, 2008. "ECG signal denoising by wavelet transform thresholding", American journal of applied science, 5(3): 276-281.

[5.] Priyanka Mundhe, A.K. Pathrikar, 2013. "An overview of implementation of efficient QRS complex detector with FPGA," International journal of advanced research in computer and communication engineering, 2(10): 4041- 4043.

[6.] Ranjana Chaturvedi, Yojana Yadav, 2013. "A survey on compression techniques for ECG signals," International journal f advanced research in computer and communication engineering, 2(9): 3511-3513.

[7.] Stojanovic, R., D. Karadaglic, M. Mirkovic, D. Milosevic, 2011. " A FPGA system for Qrs complex detection based on integer wavelet transform", Measurement science review, 11(4): 131-138.

(1) Ms. Minu Joy P. and (2) Asso. Prof. K. Thangarajan

(1) PG scholar, Embedded System Technologies, Dept of EEE RVS College of Engineering and Technology Coimbatore, Tamil Nadu, India.

(2) Department of EEE RVS College of Engineering and Technology Coimbatore, Tamil Nadu, India.

Received 25 April 2016; Accepted 28 May 2016; Available 5 June 2016

Address For Correspondence: Ms. Minu Joy P. PG scholar, Embedded System T echnologies, Dept of EEE RVS College of Engineering and T echnology Coimbatore, Tamil Nadu, India.

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Author:P., Minu Joy; Thangarajan, K.
Publication:Advances in Natural and Applied Sciences
Date:Jun 15, 2016
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