Routine use of anthelmintics can improve anaemia.
Their search identified 14 trials that could be included in their review. Data were available for 7 829 subjects, of whom 4 107 received an anthelmintic drug and 3 722 received placebo. They found that, using the World Health Organization's recommended haemoglobin cut-offs of 120 g/l in adults and 110 g/l in children, the average estimated reduction in the prevalence of anaemia ranged from 1.1% to 12.4% in adults and from 4.4% to 21.0% in children. The estimated reductions in the prevalence of anaemia increased with lower haemoglobin cut-offs used to define anaemia.
They concluded that routine administration of intestinal anthelmintic agents results in a marginal increase in haemoglobin (1.71 g/l), which could translate on a public health scale into a small (5-10%) reduction in the prevalence of anaemia in populations with a relatively high prevalence of intestinal helminths.
Gulani A et al. BMJ 2007; 334: 1095.
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|Publication:||CME: Your SA Journal of CPD|
|Article Type:||Brief article|
|Date:||Jul 1, 2007|
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