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Rosetta Biosoftware Licenses the Rosetta Resolver Expression Data Analysis System to University of Nebraska-Lincoln.

SEATTLE -- Rosetta Biosoftware announced today that University of Nebraska-Lincoln (UNL) licensed the Rosetta Resolver(R) system to study gene regulation networks at the UNL Center for Biotechnology. The Resolver system supports high-throughput gene expression studies by providing a framework that enables collaboration across entire organizations and integration with existing bioinformatics tools and resources.

"We are excited that the Rosetta Resolver system will be used to support the application of systems biology towards agricultural studies at the University of Nebraska," said Yelena Shevelenko, vice president and general manager of Rosetta Biosoftware. "The Resolver system is a scalable solution designed to support collaboration within and between organizations."

"For high-throughput plant gene expression and regulation studies, we need a highly efficient and effective workflow," said Professor Steve Ladunga at the University of Nebraska-Lincoln. "As an important part of this workflow, the Rosetta Resolver system will provide a means for sophisticated communication between several computational and experimental biologists collaborating on data-intensive projects. The Resolver system will empower us to focus on innovative research and allows us to integrate our own software development for the study of gene regulatory networks in Arabidopsis and crops as well as the chromatin remodeling events that influence gene expression."

The Rosetta Resolver system is developed and supported by Rosetta Biosoftware, and is distributed exclusively by Agilent Technologies.

About University of Nebraska-Lincoln

The role of the University of Nebraska-Lincoln,, as the primary intellectual, cultural and economic development resource for the state of Nebraska is fulfilled through the three missions of the university: teaching, research, and service. UNL pursues its missions through the Colleges of Architecture, Arts and Sciences, Business Administration, Engineering and Technology, Hixson-Lied College of Fine and Performing Arts, Education and Human Sciences, Journalism and Mass Communications, Law, the university-wide Graduate Studies, and the Institute of Agriculture and Natural Resources which includes the College of Agricultural Sciences and Natural Resources, the Agricultural Research Division, the Cooperative Extension Division, and the Conservation and Survey Division.

UNL Center for Biotechnology promotes research on all aspects of molecular life sciences research, leading to improvements in agriculture, health care and the environment. The center is supported by the Nebraska Research Initiative funds allocated through the Center for Biotechnology and by funds from the National Science Foundation (EPSCoR Infrastructure grant). For more information about the UNL Center for Biotechnology, visit

About the Rosetta Resolver System

The Rosetta Resolver system is a high-capacity data storage, retrieval, and analysis solution for gene expression data. The system is ideal for life science research organizations that need to assess compound specificity or toxicity, identify new genes or therapeutic targets or compare and analyze large databases of expression profiles. The Rosetta Resolver system combines flexibility and ease of use with high-performance algorithms to produce a comprehensive solution for rapid analysis of gene expression data. The Rosetta Resolver system can accept and analyze data from a wide variety of expression profiling formats, including Agilent DNA microarrays, and applies Rosetta Biosoftware's proprietary error models to yield quality statistics for every gene expression measurement within the system. These statistics are automatically leveraged by Rosetta Resolver system analysis tools for optimal results.

Life science research organizations that have licensed the Rosetta Resolver system include many of the top pharmaceutical companies in the world, such as Aventis Pharmaceuticals, Bristol-Myers Squibb, GlaxoSmithKline and Merck & Co., Inc., as well as premier academic institutions such as the Harvard University Center for Genomics Research and the California Institute of Technology. Additional information about the Rosetta Resolver system can be found on the Rosetta Biosoftware Web site at

About Rosetta Biosoftware

Rosetta Biosoftware is a leading provider of informatics solutions for life science research. Its comprehensive software solutions, including the Rosetta Resolver and Elucidator systems, empower life scientists with advanced, scalable, and easy-to-use analysis platforms that accelerate discovery research. Rosetta Biosoftware is a business unit of Rosetta Inpharmatics LLC, a wholly owned subsidiary of Merck & Co., Inc. (NYSE:MRK). More information about Rosetta Biosoftware is available at

Forward-Looking Statements

This press release contains "forward-looking statements" as that term is defined in the Private Securities Litigation Reform Act of 1995. These statements involve risks and uncertainties, which may cause results to differ materially from those set forth in the statements. The forward-looking statements may include statements regarding product development, product potential, or financial performance. No forward-looking statement can be guaranteed, and actual results may differ materially from those projected. Neither Rosetta Inpharmatics nor Merck & Co., Inc. undertakes any obligation to publicly update any forward-looking statement, whether as a result of new information, future events, or otherwise. Forward-looking statements in this press release should be evaluated together with the many uncertainties that affect the business of Merck & Co., Inc. including, among others, the extent to which Rosetta Inpharmatics' technology platform can be used in drug discovery programs, uncertainty of market acceptance of Rosetta Inpharmatics' technologies, ability to compete against existing technologies, and those mentioned in the cautionary statements in Item 1 of Merck's Form 10-K for the year ended Dec. 31, 2005, and in its periodic reports on Form 10-Q and Form 8-K (if any) which are incorporated by reference.

Rosetta Resolver and Elucidator are U.S. registered trademarks of Rosetta Inpharmatics LLC.
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Publication:Business Wire
Date:Jul 17, 2006
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