Printer Friendly

Rare hepatic artery anomaly (Michel type unclassified) in a patient who underwent radical gastrectomy For gastric cancer: a case report.


Hepatic artery variations are common clinical occurrences. Currently, these variations have become more important because of the increasing number of liver transplants from living donors, laparoscopic approaches for radical oncologic surgeries, and procedures such as trans arterial chemotherapy for hepatic tumors (1).

In 1928, Adachi described six types of divisions of the celiac trunk and superior mesenteric artery (SMA) based on 252 dissections of Japanese cadavers (2). In 1966, Michel et al. (3) performed a cadaver study of 200 cases and defined basic anatomic variations in hepatic arteries with only 55% standard anatomy. Hiat et al. (4) have performed 1000 cadaveric liver donor hepatic artery examination and reported 75% cases with normal anatomy. This ratio ranges from 55% to 79% in different series (1-5).

According to the Japanese guidelines, Japanese gastric cancer treatment guidelines 2010 (ver. 3) gastrohepatic ligament dissection is required for surgical treatment of gastric cancer (6). Knowing the variations that may occur in the hepatic artery during this dissection will be protective against future injury and possible postoperative complications. Possible variations observed in the contrast-enhanced three-dimensional (3D) computed tomography (CT) evaluation during the preoperative period will minimize the risk of hepatic artery injury during gastrectomy (7).

Here we aimed to present a rare hepatic artery anomaly found during preoperative CT evaluation in a patient who underwent distal subtotal gastrectomy+D2 lymph node dissection for gastric cancer.

Case report

A 66-year-old male patient was admitted to. Kartal Kosuyolu High Speciality Education and Training Hospital, Department of Gastroenterology Surgery polyclinic Kartal Kosuyolu High Speciality Training and Research Hospital with weight loss and loss of appetite, and upper gastrointestinal endoscopy indicated a diagnosis of gastric cancer in the lower third of the stomach with a pathological diagnosis of signet ring cell carcinoma. The preoperative thin-slice enhanced CT evaluation revealed a disease stage of T4N3. The images also demonstrated that the right hepatic artery (RHA) originated from SMA (Figure 1), and the left hepatic artery (LHA) was branched from the middle of the splenic artery (Figure 2). There was no common hepatic artery originating from the celiac trunk (Figure 3,4).

After preoperative neoadjuvant chemotherapy, the patient underwent laparotomy and subtotal gastrectomy with D2 lymph node dissection (LND) with a stage IIIC (T4, N3a) final pathological diagnosis. During LND, hepatic artery variations observed were that LHA branched from the splenic artery passing through anterior side of the esophagus before entering the left liver lobe and RHA originated from SMA. The patient was discharged on postoperative day 7 uneventfully.

Because the present case was studied retrospectively, no signed informed consent was taken from the patient.


During radical gastric cancer surgery, particularly in patients who underwent neoadjuvant therapy, hepatic artery injuries are observed. Main causes of hepatic artery injury are related with direct tumor invasion or lymph node metastasis. But unknown variations in the hepatic artery are also an important cause for these injuries (7).

When performing D2 LND, care must be taken in patients with variant RHA from SMA while dissecting lymph nodes 12 and 13, and care must be taken in patients with replaced LHA from any trunk while dissecting lymph nodes 1,3,7,8, and 11 (8). In the present case, we reported that there were variations in both right and left hepatic arteries and no common hepatic artery from the celiac trunk; this makes LND more difficult than that for arteries with a standard anatomy.

In different series, hepatic artery variations were reported between 21% and 45%. In 1966, Michel ret al described 10 different variations in the hepatic artery. Hiat et al. (4) modified this classification and have identified six different variations in the hepatic artery. The variation observed in the present case does not fit into any of these classifications (2-5).


The risk of hepatic artery injury during D2 LND is higher in arteries with different anatomical structures than in those with anormal variation. Detailed examination of the patients with preoperative CT evaluation and obtaining 3D angiographic image sections in case of doubt would reduce the risk of injury.

Informed Consent: Written informed consent was not obtained from patients due to the retrospective design of study.

Peer-review: Externally peer-reviewed.

Author Contributions: Concept - H.C., D.A.C.; Design - H.C., U.A.; Supervision - M.D., K.C.D.; Data Collection and/or Processing - H.C., E.G.; Analysis and/or Interpretation - H.C., D.A.C., E.G.; Literature Review - H.C., E.G., U.A.D A.C.; Writing - H.C., E.G.; Critical Review - M.D., K.C.D.

Conflict of Interest: No conflict of interest was declared by the authors.

Financial Disclosure: The authors declared that this study has received no financial support.


(1.) Abdullah SS, Mabrut JY, Garbit V, De La Roche E, Olagne E, Rode A, Morin A, et al. Anatomical variations of the hepatic artery: study of 932 cases in liver transplantation. Surgical and Radiologic Anatomy 2006; 28: 468-73. [CrossRef]

(2.) Kumari DU, Surekha T, Latha DA, Sailaja LL, Lakshmi VVV. Anomalous branching of celiac trunk-A case port. J of Evidence based Medicine and Healtcare 2015; 33: 5058-62. [CrossRef]

(3.) Michels NA. Newer anatomy of the liver and its variant blood supply and collateral circulation. The American Journal of Surgery 1966; 112: 337-347. [CrossRef]

(4.) Hiatt J R Gabbay J, Busuttil RW Surgical anatomy of the hepatic arteries in 1000 cases. Annals of surgery 1994; 220: 50. [CrossRef]

(5.) Gruttadauria S, Scotti Foglieni C, Doria C, Luca A, Lauro A, Marino IR. The hepatic artery in liver transplantation and surgery: vascular anomalies in 701 cases. Clinical transplantation. 2001; 15: 359-363. [CrossRef]

(6.) Japanese Gastric Cancer Association. Japanese gastric cancer treatment guidelines 2010 (ver. 3). Gastric cancer 2011; 14: 113-123. [CrossRef]

(7.) Huang CM, Chen QY, Lin J X, Zheng CH, Li P, Xie JW et al. Short-term clinical implications of the accessory left hepatic artery in patients undergoing radical gastrectomy for gastric cancer. PloS one. 2013; 8: e64300. [CrossRef]

(8.) Nakanishi R Endo K, Yoshinaga K, Saeki H, Morita M, Kakeji Y, Maehara Y Unique variation of the hepatic artery identified on preoperative three-dimensional computed tomography angiography in surgery for gastric cancer: report of a case. Surgery today 2010; 40: 967-971. [CrossRef]

Huseyin CIYILTEPE, Durmus Ali CETIN, Ulas ADAY, Ebubekir GUNDES, Kamuran Cumhur DEGER, Mustafa DUMAN

Gastroenterology Surgery, Kartal Kosuyolu High Specialized Training and Research Hospital Istanbul, Turkey

Cite this article as: Ciyiltepe H, Cetin DA, Aday U, Giindes E, Deger KC, Duman K. Rare Hepatic Artery Anomaly (Michel Type Unclassified) in a Patient Who Underwent Radical Gastrectomy for Gastric Cancer: a Case Report. Bezmialem Science 2017; 5:142-4.

Address for Correspondence: Hiiseyin CiYJLTEPE; Kartal Kosuyolu Yuksek ihtisas Egitim ve Arastirma Hastanesi, Gastroenteroloji Cerrahisi, istanbul, Tikkiye E-mail:

Received : 17.05.2016

Accepted : 18.07.2016

DOI: 10.14235/bs.2017.1104
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2017 Gale, Cengage Learning. All rights reserved.

Article Details
Printer friendly Cite/link Email Feedback
Title Annotation:Case Report
Author:Ciyiltepe, Huseyin; Cetin, Durmus Ali; Aday, Ulas; Gundes, Ebubekir; Deger, Kamuran Cumhur; Duman, M
Publication:Bezmialem Science
Date:Jul 1, 2017
Previous Article:An Adult Tracheocele with No Predisposing Factor.
Next Article:Effectiveness of the Capparis spinosa Treatment in Vitiligo.

Terms of use | Privacy policy | Copyright © 2021 Farlex, Inc. | Feedback | For webmasters