Pseudomonas aeruginosa bacteraemia.
In their study the most common underlying conditions were burns, HIV infection, trauma and haematological malignancies. More than a third of episodes were catheter related. In 91 bacteraemic episodes the mortality rate was 46.8% for the 79 patients whose outcome was known.
For organism-directed therapy, appropriate treatment was significantly associated with reduced mortality. Combination therapy is not necessarily more advantageous than monotherapy.
The presence of multidrug-resistant (MDR) strains and evidence of transmissions in specialised ICU facilities at the hospital suggest that the extensive use of antimicrobial agents may have played a selective role, while prolonged stay created opportunities for selection of MDR strains.
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|Publication:||South African Medical Journal|
|Article Type:||Brief article|
|Date:||Aug 1, 2008|
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