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Homeobox B9 Promotes the Progression of Hepatocellular Carcinoma via TGF-? 1/Smad and ERK1/2 Signaling Pathways. Bai, Lizhi; Ge, Pan; Zhang, Yanni; Song, Yi; Xing, Rong; Zhou, Dangxia Report Sep 16, 2022 6813
A Molecular Mechanism Study to Reveal Hirudin's Downregulation to PI3K/AKT Signaling Pathway through Decreasing PDGFR? in Renal Fibrosis Treatment. Li, Ying; Zhang, Ling; Xiong, Weijian; Gao, Xuan; Xiong, Yanying; Sun, Wei Report Sep 7, 2022 5533
Edaravone Dexborneol Alleviates Cerebral Ischemic Injury via MKP-1-Mediated Inhibition of MAPKs and Activation of Nrf2. Zhang, Wen; Yang, Haiguang; Gao, Mei; Zhang, Hengai; Shi, Lili; Yu, Xiaoyan; Zhao, Rui; Song, Junke; Report Sep 6, 2022 7459
Influence of Heat Stress on Intestinal Epithelial Barrier Function, Tight Junction Protein, and Immune and Reproductive Physiology. Ghulam Mohyuddin, Sahar; Khan, Imran; Zada, Ahmad; Qamar, Aftab; Arbab, Abdelaziz Adam Idriss; Ma, X Report Sep 1, 2022 9481
Mechanistic target of rapamycin and an extracellular signaling-regulated kinases 1 and 2 signaling participate in the process of acetate regulating lipid metabolism and hormone-sensitive lipase expression. Li, Yujuan; Fu, Chunyan; Liu, Lei; Liu, Yongxu; Li, Fuchang Report Sep 1, 2022 4934
LKB1 suppression promotes cardiomyocyte regeneration via LKB1-AMPK-YAP axis. Qu, Shuang; Liao, Qiao; Yu, Cheng; Chen, Yue; Luo, Hao; Xia, Xuewei; He, Duofen; Xu, Zaicheng; Jose, Sep 1, 2022 5836
Comparison of Transcriptomic Signatures between Monkeypox-Infected Monkey and Human Cell Lines. Xuan, Do Thi Minh; Yeh, I-Jeng; Wu, Chung-Che; Su, Che-Yu; Liu, Hsin-Liang; Chiao, Chung-Chieh; Ku, Sep 1, 2022 8803
SLC26A4 Mutation Promotes Cell Apoptosis by Inducing Pendrin Transfer, Reducing Cl[sup.-] Transport, and Inhibiting PI3K/Akt/mTOR Pathway. Dai, Xiang; Li, Jun; Hu, XiJiang; Ye, Jian; Cai, WenQian Report Aug 29, 2022 5009
Fluoride Exposure Suppresses Proliferation and Enhances Endoplasmic Reticulum Stress and Apoptosis Pathways in Hepatocytes by Downregulating Sirtuin-1. Yu, Yanlong; Li, Ling; Yu, Wenfeng; Guan, Zhizhong Report Aug 21, 2022 6407
Long Noncoding RNA LEMD1-AS1 Increases LEMD1 Expression and Activates PI3K-AKT Pathway to Promote Metastasis in Oral Squamous Cell Carcinoma. Li, Zaiye; Wang, Jie; Wu, Jianjun; Li, Ning; Jiang, Canhua Report Aug 9, 2022 6726
FLOT2 Promotes the Proliferation and Epithelial-mesenchymal Transition of Cervical Cancer by Activating the MEK/ERK1/2 Pathway. Li, Yang; Dou, Shulan Report Aug 1, 2022 3472
PLK1 Is a Potential Prognostic Factor Associated with the Tumor Microenvironment in Lung Adenocarcinoma. Wang, Lina; Gao, Man; Sun, Dongjie; Wu, Haitao; Lv, Shuang; Li, Yulin; Li, Lisha Report Jul 30, 2022 6598
Comprehensive Expression Profiling and Molecular Basis of CDC28 Protein Kinase Regulatory Subunit 2 in Cervical Cancer. Qin, Li; Luo, Xiaoqiong; Qin, Xiao; Huang, Hongbao; Zhang, Lianling; Chen, Shengcai; Wu, Xiaoqin Jul 28, 2022 5588
Adropin Inhibits Vascular Smooth Muscle Cell Osteogenic Differentiation to Alleviate Vascular Calcification via the JAK2/STAT3 Signaling Pathway. Wang, Li; Jin, Fulu; Wang, Peiyu; Hou, Shiqiang; Jin, Tao; Chang, Xiansong; Zhao, Liangping Report Jul 27, 2022 5307
Dapagliflozin Improves Diabetic Cardiomyopathy by Modulating the Akt/mTOR Signaling Pathway. Ren, Mengxiang; Pan, Dabin; Zha, Dayong; Shan, Zeyang Report Jul 26, 2022 7214
Resveratrol Synergistically Promotes BMP9-Induced Osteogenic Differentiation of Mesenchymal Stem Cells. Wang, Yonghui; Xia, Chao; Chen, Yang; Jiang, Tianyuan; Hu, Yan; Gao, Yanhong Jul 25, 2022 8636
INTER-POPULATION COMPARISONS AND THE IMPORTANCE IN INFECTIOUS DISEASES OF THE IRF7, TBK1, IFNAR1, IFNAR2 AND TLR3 GENE VARIANTS IN TURKISH INDIVIDUALS/ TURK POPULASYONUNDA IRF7, TBK1, IFNAR1, IFNAR2 VE TLR3 GEN VARYANTLARININ POPULASYONLAR ARASI KARSILASTIRMALARI VE ENFEKSIYON HASTALIKLARINDAKI ONEMI. Karacan, Asli; Toksoy, Guven; Uyguner, Oya; Karaman, Birsen; Basaran, Seher; Komurcu-Bayrak, Evrim Report Jul 23, 2022 7075
Mechanical Stretch Promotes Macrophage Polarization and Inflammation via the RhoA-ROCK/NF-? B Pathway. Tu, Peng-cheng; Pan, Ya-lan; Liang, Zhong-qing; Yang, Guang-lu; Wu, Cheng-jie; Zeng, Liang; Wang, Li Report Jul 23, 2022 5594
Berberine Attenuates IL-1? -Induced Damage of Nucleus Pulposus Cells via Activating the AMPK/mTOR/Ulk1 Pathway. Huang, Liaoyuan; Chen, Jianming; Wu, Danhai; Wang, Kan; Lou, Weigang; Wu, Jianmin Report Jul 23, 2022 6424
Reveal the Mechanisms of Yi-Fei-Jian-Pi-Tang on Covid-19 through Network Pharmacology Approach. Lang, Wanying; Yang, Feng; Cai, Fanfan; Shi, Wengui; Dong, Min; An, Qi; Li, Yanping Jul 16, 2022 5342
Anti-Inflammatory Effects of Phlebia sp. Extract in Lipopolysaccharide-Stimulated RAW 264.7 Macrophages. Lim, Eui Hyeon; Mun, Seul-Ki; Kim, Jong-Jin; Chang, Dong-Jo; Yee, Sung-Tae Report Jul 14, 2022 4955
SLC6A14 Depletion Contributes to Amino Acid Starvation to Suppress EMT-Induced Metastasis in Gastric Cancer by Perturbing the PI3K/AKT/mTORC1 Pathway. Guo, Qie; Xu, Wen; Li, Xiao; Sun, Jia-Lin; Gu, Xiao-Ce; Jing, Fan-Bo Report Jul 12, 2022 8279
Proteomic Analysis Reveals the Vital Role of Synaptic Plasticity in the Pathogenesis of Temporal Lobe Epilepsy. Qian, Xu; Ding, Ji-Qiang; Zhao, Xin; Sheng, Xin-Wen; Wang, Zhao-Rui; Yang, Qi-xing; Zheng, Jing-Jun Jul 11, 2022 7578
Linalool Impress Colorectal Cancer Deterioration by Mediating AKT/mTOR and JAK2/STAT3 Signaling Pathways. Hou, Min; Zhang, Yakun; Huang, Qingmei; Zhan, Hongmei; Jia, Tingting; Li, Min; Hu, Jing; Zhao, Yanli Report Jul 11, 2022 4472
lncRNA MEG3 Inhibits the Proliferation and Growth of Glioma Cells by Downregulating Bcl-xL in the PI3K/Akt/NF-? B Signal Pathway. Jia, Haibo; Yan, Xiaoxiao Report Jul 11, 2022 6568
SBP-0636457, a Novel Smac Mimetic, Cooperates with Doxorubicin to Induce Necroptosis in Breast Cancer Cells during Apoptosis Blockage. Yu, Rui; Wang, Lei; Ji, Xiaochun; Mao, Chenxiao Jul 11, 2022 5067
Effect and Mechanism of Yisui Fuyongtang (YSFYT) Decoction on Cognitive Function and Synaptic Plasticity in Rats with Vascular Cognitive Impairment. Gong, Tingliang; Luo, Zhaoliang; Huang, Li; Xiao, Caixian; Yi, Junlu; Yan, Junfeng; Chen, Qian Jul 8, 2022 8777
The highly pathogenic H5N1 avian influenza virus induces the mitogen-activated protein kinase signaling pathway in the trachea of two Ri chicken lines. Vu, Thi Hao; Hong, Yeojin; Truong, Anh Duc; Lee, Sooyeon; Heo, Jubi; Lillehoj, Hyun S.; Hong, Yeong Report Jul 1, 2022 5636
Magnoliae flos Downregulated Lipopolysaccharide-Induced Inflammatory Responses via NF-? B/ERK-JNK MAPK/STAT3 Pathways. Gil, Tae-Young; Jin, Bo-Ram; Cha, Yun-Yeop; An, Hyo-Jin Jun 26, 2022 6256
Maackiain Prevents Amyloid-Beta-Induced Cellular Injury via Priming PKC-Nrf2 Pathway. Lu, Na; Tan, Guojun; Tan, Hongling; Zhang, Xing; Lv, Yunling; Song, Xiujuan; You, Daofeng Report Jun 22, 2022 5213
Protein Kinase Inhibition, Antibacterial Activity, and Characterization of Phytoextract-Mediated Silver Nanoparticles Using Aqueous Extracts of Ifloga spicata. Gul, Ahmad; Wahab, Abdul; Fozia, Fozia; Shah, Syed Majid; Gul, Rukhsana; Ali, Jamshed; Khan, Nauman Jun 16, 2022 6355
The Bioactivities of Phycocyanobilin from Spirulina. Li, Yi Jun 11, 2022 7374
Alpha-Lipoic Acid Promotes Intestinal Epithelial Injury Repair by Regulating MAPK Signaling Pathways. Yang, Yu; Xiao, Yong; Jiang, Yue; Luo, Jiajun; Yuan, Jingwen; Yan, Junfeng; Tong, Qiang Jun 7, 2022 4031
Molecular Mechanisms of Hawthorn Extracts in Multiple Organs Disorders in Underlying of Diabetes: A Review. Gheitasi, Izadpanah; Savari, Feryal; Akbari, Ghaidafeh; Mohammadi, Jamshid; Fallahzadeh, Ali Reza; S Jun 7, 2022 10813
Sequential Development of [JAK2.sup.V617F] Mutation and BCR-ABL1 Fusion in Individual Patients With Myeloproliferative Neoplasms: A Linear Clonal Evolution or Parallel Clonal Competition? Zhao, Yue; Reddi, Deepti; McCracken, Jenna; Iranzad, Natasha; Rehder, Cathrine; Neff, Jadee; Wang, E Report Jun 1, 2022 5384
Marine-Derived Stichloroside C2 Inhibits Epithelial-Mesenchymal Transition and Induces Apoptosis through the Mitogen-Activated Protein Kinase Signalling Pathway in Triple-Negative Breast Cancer Cells. Cui, Chuang; Ding, Chen-Huan; Liu, Fang-Fang; Lu, Jing-Rong; Zheng, Shi-Yun; Lin, Hou-Wen; Zhu, Wei- May 14, 2022 6791
Forskolin Stimulates Estrogen Receptor (ER) a Transcriptional Activity and Protects ER from Degradation by Distinct Mechanisms. Tsai, Houng-Wei; Lin, Vicky Y.; Shupnik, Margaret A. May 9, 2022 13226
KIF22 Promotes Development of Pancreatic Cancer by Regulating the MEK/ERK/P21 Signaling Axis. Zhang, Ruiyun; Ma, Li; Wei, Yucai; Wei, Kongkong; Song, Tianliang; Du, Zhixing; Feng, Zhijun Report May 6, 2022 4273
6[sup.?]-O-Galloylpaeoniflorin Exerts Inhibitory Bioactivities in Human Neuroblastoma Cells via Modulating AMPK/miR-489/XIAP Pathway. Zhou, Lijun; Li, Aiwu; Zhang, Qiangye Report May 5, 2022 5862
Cellular Localization of MAPK, NF-KB and Nrf2 Signaling Pathways-Related Proteins in Crayfish hepatopancreas. Wei, Keqiang; Wei, Yue; Song, Changxia Report Apr 30, 2022 2773
Baicalin Attenuated A? [sub.1-42]-Induced Apoptosis in SH-SY5Y Cells by Inhibiting the Ras-ERK Signaling Pathway. Song, Zhenyan; He, Chunxiang; Yu, Wenjing; Yang, Miao; Li, Ze; Li, Ping; Zhu, Xu; Xiao, Chen; Cheng, Report Apr 27, 2022 7175
Molecular Hydrogen Inhibits Colorectal Cancer Growth via the AKT/SCD1 Signaling Pathway. Zhang, Xiangyan; Tao, Geru; Zhao, Ya'nan; Xing, Sijie; Jiang, Jie; Liu, Boyan; Qin, Shucun Report Apr 26, 2022 7014
Immunotherapy Mechanism of Esophageal Squamous Cell Carcinoma with the Effect of STK11/AMPK Signaling Pathway. Xia, Yang; Wang, Peng; Ye, Yunyao; Zhang, Sihui; Sun, Guangzhi; Xu, Jie; Han, Gaohua Report Apr 15, 2022 5223
a -Bisabolol Mitigates Colon Inflammation by Stimulating Colon PPAR-? Transcription Factor: In Vivo and In Vitro Study. Venkataraman, Balaji; Almarzooqi, Saeeda; Raj, Vishnu; Dudeja, Pradeep K.; Bhongade, Bhoomendra A.; Apr 13, 2022 10106
Provectus announces presentation of multiple protein kinase signaling targets. Apr 11, 2022 243
Sex-dependent effects of resveratrol and regular exercise on markers related to cellular stress in the hearts and kidneys of rats. Bal, Nur Banu; Han, Sevtap; Usanmaz, Suzan Emel; Uludag, Mecit Orhan; Yilmaz, Emine Demirel Apr 1, 2022 6682
Sex-dependent effects of resveratrol and regular exercise on markers related to cellular stress in the hearts and kidneys of rats. Bal, Nur Banu; Han, Sevtap; Usanmaz, Suzan Emel; Uludag, Mecit Orhan; Yilmaz, Emine Demirel Apr 1, 2022 6148
Inhibition of Axl Promotes the Therapeutic Effect of Targeted Inhibition of the PI3K/Akt Pathway in NRAS Mutant Melanoma Cells. Gao, Xuejun; Xue, Dandan; Cheng, Jingjing; Zhang, Xin; Cai, Xia Mar 11, 2022 5679
Licochalcone A Promotes the Ubiquitination of c-Met to Abrogate Gefitinib Resistance. Han, Shuangze; Li, Xiaoying; Gan, Yu; Li, Wei Report Mar 10, 2022 7516
Effects and Mechanism of Ganoderma lucidum Polysaccharides in the Treatment of Diabetic Nephropathy in Streptozotocin-Induced Diabetic Rats. Hu, Yu; Wang, Shu-Xiang; Wu, Fu-Yu; Wu, Ke-Jia; Shi, Rui-Ping; Qin, Li-Hong; Lu, Chun-Feng; Wang, Sh Report Mar 8, 2022 9082
Fuzheng Jiedu Decoction Induces Apoptosis and Enhances Cisplatin Efficacy in Ovarian Cancer Cells In Vitro and In Vivo through Inhibiting the PI3K/AKT/mTOR/NF-? B Signaling Pathway. Yang, Huadi; Li, Hui; Lu, Shenyi; Shan, Shuangshuang; Guo, Yong Report Mar 2, 2022 6471
Curcumin Analogues as Promissory Compounds for Inhibition of [beta]-Secretase, [gamma]-Secretase and GSK-3[BETA] Implicated at Alzheimer Disease: In Silico Study. Contreras-Puentes, Neyder; Perez-Orozco, Daimer; Camacho-Diaz, Fernando Report Mar 1, 2022 3413
EVALUATION OF PTEN AND PI3K/AKT EXPRESSIONS IN STANOZOLOL-TREATED RAT KIDNEYS/STANOZOLOL UYGULANAN SICAN BOBREGINDE PTEN VE PI3K/AKT EMPRESYONLARININ DEGERLENDIRILMESI. Kotil, Tugba; Sevim, Cigdem; Kara, Mehtap Report Mar 1, 2022 4358
T1AM Attenuates the Hypoxia/Reoxygenation-Induced Necroptosis of H9C2 Cardiomyocytes via RIPK1/RIPK3 Pathway. Wei, Bo; Zhao, Hanbing; Hu, Bailong; Dai, Lujun; Zhang, Guoning; Mo, Lili; Huang, Niwen Report Feb 28, 2022 3637
Bixin Prevents Colorectal Cancer Development through AMPK-Activated Endoplasmic Reticulum Stress. Qiu, Yunfeng; Li, Changfeng; Zhang, Bin Report Feb 24, 2022 5311
Implications of glutathione-S transferase P1 in MAPK signaling as a CRAF chaperone: In memory of Dr. Irving Listowsky. Niitsu, Yoshiro; Sato, Yasushi; Takayama, Tetsuji Feb 1, 2022 9199
Phosphorylation at Ser 727 Increases STAT3 Interaction with PKCε Regulating Neuron-Glia Crosstalk via IL-6-Mediated Hyperalgesia In Vivo and In Vitro. Li, Xiongjuan; Zhou, Biqiang; Yang, Han; Yang, Xinping; Zhao, Zhao; Pan, Zhenglong; Liao, Xinran Jan 28, 2022 7273
Mechanism of Gegen Qinlian Decoction Regulating ABTB1 Expression in Colorectal Cancer Metastasis Based on PI3K/AKT/FOXO1 Pathway. Li, Feng; Chen, Lili; Zheng, Jinzhou; Yang, Jianfeng; Song, Xiaoyun; Wang, Yu; Zhou, Xiqiu Report Jan 24, 2022 3909
Molecular Mechanism of Tetramethylpyrazine Ameliorating Neuroexcitotoxicity through Activating the PKA/CREB Signaling Pathway. Tong, Hongxuan; Wang, Kaili; Wang, Xiting; Lu, Tao Report Jan 20, 2022 5504
Effects and Mechanism of Oxymatrine Combined with Compound Yinchen Granules on the Apoptosis of Hepatocytes through the Akt/FoxO3a/Bim Pathway. Zhang, Xian; Ge, Jiajia; Zhu, Xuejuan; Zhang, Haifeng; Wang, Yuanzi; Xu, Tongtong; Jiang, Wei Report Jan 6, 2022 5586
The Effect of Type 2 Diabetes Mellitus on the Development of Alzheimer's Disease and Its Molecular Mechanism/Tip 2 Diabetes Mellitus'un Alzheimer Hastaliginin Gelisimindeki Etkisi ve Molekuler Mekanizmalari. Duran, Rabia; Pancur, Sumeyra; Bahadori, Fatemeh Report Jan 1, 2022 6305
Interfering with pak4 Protein Expression Affects Osteosarcoma Cell Proliferation and Migration. Fu, Yuxin; Fang, Lun; Yin, Qipu; Wu, Qi; Sui, Wei; Sun, Ying; Zhao, Xindi Report Dec 30, 2021 4703
AMPK, Aging, and Belly Fat. McCulloch, Marsha Dec 22, 2021 2074
Mechanism and Protection of Radiotherapy Induced Sensorineural Hearing Loss for Head and Neck Cancer. Shi, Wenxia; Hou, Xue; Bao, Xueying; Hou, Wei; Jiang, Xuehua; Ma, Lixin; Jiang, Xin; Dong, Lihua Report Dec 21, 2021 8741
Differences of Key Proteins between Apoptosis and Necroptosis. Park, Min Yeong; Ha, Sang Eun; Vetrivel, Preethi; Kim, Hun Hwan; Bhosale, Pritam Bhangwan; Abusaliya Report Dec 12, 2021 5929
The Clinical Significance and Potential Molecular Mechanism of Upregulated CDC28 Protein Kinase Regulatory Subunit 1B in Osteosarcoma. Mo, Chaohua; Xie, Le; Chen, Chang; Ma, Jie; Huang, Yingxin; Wu, Yanxing; Xu, Yuanyuan Dec 10, 2021 12208
Aprepitant Promotes Caspase-Dependent Apoptotic Cell Death and G2/M Arrest through PI3K/Akt/NF-? B Axis in Cancer Stem-Like Esophageal Squamous Cell Carcinoma Spheres. Javid, Hossein; Afshari, Amir R.; Zahedi Avval, Farnaz; Asadi, Jahanbakhsh; Hashemy, Seyed Isaac Report Dec 9, 2021 6697
Bevacizumab Increases Endothelin-1 Production via Forkhead Box Protein O1 in Human Glomerular Microvascular Endothelial Cells In Vitro. Nihei, Satoru; Asaka, Junichi; Takahashi, Hiroaki; Kudo, Kenzo Dec 6, 2021 4899
Structural Diversity and Role of Phytochemicals against P38-[alpha] Mitogen-activated Protein Kinase and Epidermal Growth Factor Receptor Kinase Domain: A Privileged Computational Approach. Shankar, Amar; Gopinath, S.M.; Kollur, Shiva Prasad; Sushma, P.; Jain, Anisha S.; Patil, Sharanagoud Dec 1, 2021 2555
Discovery of Novel Pyruvate Kinase Inhibitors Against Leishmania major Among FDA Approved Drugs Through System Biology and Molecular Docking Approach/Sistem Biyolojisi ve Molekuler Yerlestirme Yaklasimi Yoluyla FDA Onayli Ilaclar Arasinda Leishmania major'a Karsi Yeni Piruvat Kinaz Inhibitorlerinin Kesfi. Amiri-Dashatan, Nasrin; Rezaei-Tavirani, Mostafa; Ranjbar, Mohammad Mehdi; Koushki, Mehdi; Nasab, Se Report Dec 1, 2021 3650
Genetic Features and TP53 Mutations in Chronic Lymphocytic Leukemia/ Kronik Lenfositik Losemide Genetik Ozellikler ve TP53 Mutasyonu. Ozunal, Isil Erdogan; Elverdi, Tugrul; Salihoglu, Ayse; Eskazan, Ahmet Emre; Ar, Muhlis Cem; Ongoren Dec 1, 2021 3503
In silico Docking Studies of Antiglycation Activity of Isorhamnetin on Molecular Proteins of Advanced Glycation end Product (AGE) Pathway. Sindhuja, A.; Vimalavathini, R.R.; Kavimani, S. Report Dec 1, 2021 3750
Downregulation of RIP3 Improves the Protective Effect of ATF6 in an Acute Liver Injury Model. Huang, Mei-Ying; Wan, Dian-Wei; Deng, Jie; Guo, Wen-Jie; Huang, Yue; Chen, Huan; Xu, De-Lin Report Nov 5, 2021 7940
Genome-wide identification and analysis of long noncoding RNAs in longissimus muscle tissue from Kazakh cattle and Xinjiang brown cattle. Yan, Xiang-Min; Zhang, Zhe; Liu, Jian-Bo; Li, Na; Yang, Guang-Wei; Luo, Dan; Zhang, Yang; Yuan, Bao; Report Nov 1, 2021 4924
Knockdown of Serum- and Glucocorticoid-Regulated Kinase 1 Enhances Cisplatin Sensitivity of Gastric Cancer Through Suppressing the Nuclear Factor Kappa-B Signaling Pathway. Zhang, Jishui; Lv, Wenhao; Liu, Yagang; Fu, Weihua; Chen, Baosheng; Ma, Qiutong; Gao, Xin; Cui, Xiux Report Nov 1, 2021 3993
Targeting PINK1 Using Natural Products for the Treatment of Human Diseases. Li, Yan-Qin; Zhang, Fan; Yu, Li-Ping; Mu, Jian-Kang; Yang, Ya-Qin; Yu, Jie; Yang, Xing-Xin Report Oct 30, 2021 7491
ADAM17 Mediates Hypoxia-Induced Keratinocyte Migration via the p38/MAPK Pathway. Zhu, Guoqin; Liu, Jie; Wang, Yuan; Jia, Naixin; Wang, Weiyi; Zhang, Junhui; Liang, Yi; Tian, Hao; Zh Report Oct 28, 2021 6022
Synergistic Antiproliferative Effects of All-Trans Retinoic Acid and Paclitaxel on Autosomal Dominant Polycystic Kidney Disease Epithelial Cells. Nguyen, Que Thanh Thanh; Hoang, Thi Xoan; Ryu, Hyunjin; Oh, Kook-Hwan; Kim, Jae Young Report Oct 6, 2021 6742
Anti-influenza A Virus Effects and Mechanisms of Emodin and Its Analogs via Regulating PPAR? /? -AMPK-SIRT1 Pathway and Fatty Acid Metabolism. Bei, Yufei; Tia, Boyu; Li, Yuze; Guo, Yingzhu; Deng, Shufei; Huang, Rouyu; Zeng, Huiling; Li, Rui; W Report Sep 9, 2021 8205
B-RAF V600E AND B-RAF CODON 464-469 MUTATIONS IN HAIRY CELL LEUKEMIA PATIENTS AND THEIR RELATION WITH CLINICAL PARAMETERS. Olgun, Aybuke; Basbinar, Yasemin; Alacacioglu, Inci; Solmaz, Serife; Akbarpour, Mahdi; Uysal, Tugba Sep 1, 2021 3484
Effects of the Rho/Rho-Kinase Pathway on Perfusion Pressure in the Isolated-Perfused Rat Hind Limb Vascular Bed. Ilhan, Esra; Büyükafsar, Kansu; Tiftik, R. Nalan; Secilmis, M. Ata; Alzayed, Zayed Report Sep 1, 2021 3874
miR-143-3p Inhibits the Differentiation of Osteoclast Induced by Synovial Fibroblast and Monocyte Coculture in Adjuvant-Induced Arthritic Rats. Jiang, Baoping; Yuan, Chengchen; Han, Jing; Shen, Meiyu; Zhou, Xueping; Zhou, Lingling Report Aug 27, 2021 5350
Exploring the Pharmacological Mechanisms of Tripterygium wilfordii Hook F against Cardiovascular Disease Using Network Pharmacology and Molecular Docking. Huang, Bingwu; Huang, Chengbin; Zhu, Liuyan; Xie, Lina; Wang, Yi; Zhu, Ning Report Aug 16, 2021 6717
Effect of MiR-210 on the Chemosensitivity of Breast Cancer by Regulating JAK-STAT Signaling Pathway. Xing, Zeyu; Wang, Xin; Liu, Jiaqi; Liu, Gang; Zhang, Menglu; Feng, Kexin; Wang, Xiang Report Aug 11, 2021 4725
miR-339-5p Inhibits Autophagy to Reduce the Resistance of Laryngeal Carcinoma on Cisplatin via Targeting TAK1. Li, Guang; Cheng, Zexing Report Aug 4, 2021 4811
Investigation of the Role of Neurokinin-1 Receptor Inhibition Using Aprepitant in the Apoptotic Cell Death through PI3K/Akt/NF-? B Signal Transduction Pathways in Colon Cancer Cells. Ghahremanloo, Atefeh; Javid, Hossein; Afshari, Amir R.; Hashemy, Seyed Isaac Report Aug 3, 2021 6338
Stomach-specific c-Myc overexpression drives gastric adenoma in mice through AKT/mammalian target of rapamycin signaling. Liu, Jing; Feng, Wenxin; Liu, Min; Rao, Hanyu; Li, Xiaoxue; Teng, Yan; Yang, Xiao; Xu, Jin; Gao, Wei Report Aug 1, 2021 6438
Effects of Ulinastatin on Proliferation and Apoptosis of Breast Cancer Cells by Inhibiting the ERK Signaling Pathway. Xing, Zeyu; Wang, Xin; Liu, Jiaqi; Liu, Gang; Zhang, Menglu; Feng, Kexin; Wang, Xiang Report Jul 31, 2021 3789
Multiomics Profiling and Clustering of Low-Grade Gliomas Based on the Integrated Stress Status. Ren, Xiaolin; Chen, Xin; Zhu, Chen; Wu, Anhua Report Jul 29, 2021 6136
Immunoinformatic Analysis of Calcium-Dependent Protein Kinase 7 (CDPK7) Showed Potential Targets for Toxoplasma gondii Vaccine. Taghipour, Ali; Tavakoli, Sanaz; Sabaghan, Mohamad; Foroutan, Masoud; Majidiani, Hamidreza; Soltani, Report Jul 12, 2021 7143
PICK1 Deficiency Exacerbates Sepsis-Associated Acute Kidney Injury. Dou, Qian; Tong, Hang; Yang, Yichun; Zhang, Han; Gan, Hua Report Jul 9, 2021 6017
miR-451 on Myocardial Ischemia-Reperfusion in Rats by Regulating AMPK Signaling Pathway. Guo, Yulin; Gao, Jie; Liu, Yan; Zhang, Xitao; An, Xiangguang; Zhou, Jian; Su, Pixiong Report Jul 7, 2021 7111
Role of stearyl-coenzyme A desaturase 1 in mediating the effects of palmitic acid on endoplasmic reticulum stress, inflammation, and apoptosis in goose primary hepatocytes. Tang, Bincheng; Qiu, Jiamin; Hu, Shenqiang; Li, Liang; Wang, Jiwen Report Jul 1, 2021 5254
Exosomes of Mesenchymal Stem Cells as a Proper Vehicle for Transfecting miR-145 into the Breast Cancer Cell Line and Its Effect on Metastasis. Sheykhhasan, Mohsen; Kalhor, Naser; Sheikholeslami, Azar; Dolati, Masoumeh; Amini, Elaheh; Fazaeli, Report Jun 30, 2021 8802
Overexpression of Long Noncoding RNA H19 Downregulates miR-140-5p and Activates PI3K/AKT Signaling Pathway to Promote Invasion, Migration and Epithelial-Mesenchymal Transition of Ovarian Cancer Cells. Xu, Hao; Ding, Yuan; Yang, Xiangying Report Jun 21, 2021 5926
Overexpression of RIPK4 Predicts Poor Prognosis and Promotes Metastasis in Ovarian Cancer. Liu, Shaoqiu; He, Lewei; Sheng, Chenchen; Su, Rongjia; Wu, Xiaomei; Sun, Yunyan; Xi, Xiaowei Report Jun 3, 2021 4877
Zearalenone exposure affects the Wnt/[beta]-catenin signaling pathway and related genes of porcine endometrial epithelial cells in vitro. Song, Tingting; Yang, Weiren; Huang, Libo; Yang, Zaibin; Jiang, Shuzhen Jun 1, 2021 6429
NEWS BRIEFS. May 28, 2021 679
Isovitexin Suppresses Stemness of Lung Cancer Stem-Like Cells through Blockage of MnSOD/CaMKII/AMPK Signaling and Glycolysis Inhibition. Liu, Fei; Yuan, Qing; Cao, Xiaocheng; Zhang, Jinlin; Cao, Jianguo; Zhang, Jiansong; Xia, Liqiu Report May 24, 2021 6765
Analysis of the Efficacy and Mechanism of Action of Xuebijing Injection on ARDS Using Meta-Analysis and Network Pharmacology. Zhang, Yun; Wang, Jie; Liu, Yong-Mei; Yang, Hui; Wu, Guang-Jun; He, Xuan-Hui Report May 24, 2021 6116
The Kidney-Related Effects of Polystyrene Microplastics on Human Kidney Proximal Tubular Epithelial Cells HK-2 and Male C57BL/6 Mice. Wang, Yung-Li; Lee, Yu-Hsuan; Hsu, Yung-Ho; Chiu, I-Jen; Huang, Cathy Chia-Yu; Huang, Chih-Chia; Chi Report May 1, 2021 15937
Combined inhibition of ACK1 and AKT shows potential toward targeted therapy against KRAS-mutant non-small-cell lung cancer. Yu, Xiangjing; Liu, Jie; Qiu, Huawei; Hao, Huiting; Zhu, Jinhong; Peng, Shiyun Report May 1, 2021 5794
The Use of BT-ESD Technology under General Intravenous Anesthesia in the Treatment of Nonmuscle Invasive Bladder Cancer and the Effect of PI3K/Akt Signaling Pathway on Tumor Recurrence. Yan, Haiyan; Xia, Shunyao; Yao, Dayong; Shi, Jinghui; Liu, Zan Report Apr 26, 2021 4634
IL-6 Promotes the Proliferation and Immunosuppressive Function of Myeloid-Derived Suppressor Cells via the MAPK Signaling Pathway in Bladder Cancer. Zheng, Zhong; Zheng, Xinyi; Zhu, Yiwen; Yao, Zhixian; Zhao, Weiguang; Zhu, Youjia; Sun, Feng; Mu, Xi Report Apr 24, 2021 6725
Molecular Mechanism of Expression Changes of Immunological Indexes of PD-1/sPD-L1 after Radiotherapy in Nonsmall Cell Lung Cancer. Qu, Yanli; Wang, Huan; Liu, Hangyu; Sun, Xiaohu; Li, Ji; Yu, Hong Report Apr 20, 2021 5183
Fisetin Attenuates Lipopolysaccharide-Induced Inflammatory Responses in Macrophage. Hada, Yoshiko; Uchida, Haruhito A.; Wada, Jun Report Apr 13, 2021 5364
Assessing the Association of Mitochondrial Function and Inflammasome Activation in Murine Macrophages Exposed to Select Mitotoxic Tri-Organotin Compounds. (Research). Childers, Gabrielle M.; Perry, Caroline A.; Blachut, Barbara; Martin, Negin; Bortner, Carl D.; Siebe Report Apr 1, 2021 26754
Human Schlafen 5 Inhibits Proliferation and Promotes Apoptosis in Lung Adenocarcinoma via the PTEN/PI3K/AKT/mTOR Pathway. Gu, Xuefeng; Zhou, Li; Chen, Lei; Pan, Huiqing; Zhao, Rui; Guang, Weiwei; Wan, Guoqing Report Mar 23, 2021 6477
H[sub.2]O[sub.2]-Driven Anticancer Activity of Mn Porphyrins and the Underlying Molecular Pathways. Batinic-Haberle, Ines; Tovmasyan, Artak; Huang, Zhiqing; Duan, Weina; Du, Li; Siamakpour-Reihani, Sh Mar 15, 2021 20478
Therapeutic Potential of RTA 404 in Human Brain Malignant Glioma Cell Lines via Cell Cycle Arrest via p21/AKT Signaling. Tsai, Tai-Hsin; Lieu, Ann-Shung; Wang, Yi-Wen; Yang, Sheau-Fang; Hsu, Yi-Chiang; Lin, Chih-Lung Report Mar 9, 2021 6857
Upregulation of CDC7 Associated with Cervical Cancer Incidence and Development. Wang, Qingwei; Zheng, Weiping Report Mar 4, 2021 4460
Focal Adhesion Kinase Inhibitor Inhibits the Oxidative Damage Induced by Central Venous Catheter via Abolishing Focal Adhesion Kinase-Protein Kinase B Pathway Activation. Wang, Yanru; Lin, Sulan; Jiang, Ping; Song, Yunlin; Zhao, Yanjie; Zheng, Yujian Report Mar 2, 2021 6957
Effects of lycopene on abdominal fat deposition, serum lipids levels and hepatic lipid metabolism-related enzymes in broiler chickens. Wan, Xiaoli; Yang, Zhengfeng; Ji, Haoran; Li, Ning; Yang, Zhi; Xu, Lei; Yang, Haiming; Wang, Zhiyue Report Mar 1, 2021 4915
miR-92a-3p promotes ox-LDL induced-apoptosis in HUVECs via targeting SIRT6 and activating MAPK signaling pathway. Xu, Yingchun; Miao, Chunbo; Cui, Jinzhen; Bian, Xiaoli Feb 19, 2021 4358
The role of glycogen synthase kinase 3 (GSK3) in cancer with emphasis on ovarian cancer development and progression: A comprehensive review. Glibo, Mislav; Serman, Alan; Karin-Kujundzic, Valentina; Vlatkovic, Ivanka Bekavac; Miskovic, Berivo Report Feb 1, 2021 10795
The Polymethoxy Flavonoid Sudachitin Inhibits Interleukin-1? -Induced Inflammatory Mediator Production in Human Periodontal Ligament Cells. Hosokawa, Yoshitaka; Hosokawa, Ikuko; Ozaki, Kazumi; Matsuo, Takashi Report Jan 29, 2021 3138
Downregulation of microRNA-15b-5p Targeting the Akt3-Mediated GSK-3? /? -Catenin Signaling Pathway Inhibits Cell Apoptosis in Parkinson's Disease. Zhu, Jianzhong; Xu, Xue; Liang, Yingyin; Zhu, Ronglan Report Jan 6, 2021 5998
Proanthocyanidins as a Potential Novel Way for the Treatment of Hemangioma. Tang, Ran; Xian, Dehai; Xu, Jixiang; Peng, Huiling; Pan, Shihong; Zhong, Jianqiao Report Jan 2, 2021 7444
Therapeutic Potential of RTA 404 in Human Brain Malignant Glioma Cell Lines via Cell Cycle Arrest via p21/AKT Signaling. Tsai, Tai-Hsin; Lieu, Ann-Shung; Wang, Yi-Wen; Yang, Sheau-Fang; Hsu, Yi-Chiang; Lin, Chih-Lung Report Jan 1, 2021 6859
Bcl-2 Is Involved in Cardiac Hypertrophy through PI3K-Akt Pathway. Meng, Xianwei; Cui, Jun; He, Guibin Report Jan 1, 2021 4169
ROS-ERK Pathway as Dual Mediators of Cellular Injury and Autophagy-Associated Adaptive Response in Urinary Protein-Irritated Renal Tubular Epithelial Cells. Deng, Jian-kun; Zhang, Xueqin; Wu, Hong-luan; Gan, Yu; Ye, Ling; Zheng, Huijuan; Zhu, Zebing Jan 1, 2021 4559
Focal Adhesion Kinase Inhibitor Inhibits the Oxidative Damage Induced by Central Venous Catheter via Abolishing Focal Adhesion Kinase-Protein Kinase B Pathway Activation. Wang, Yanru; Lin, Sulan; Jiang, Ping; Song, Yunlin; Zhao, Yanjie; Zheng, Yujian Report Jan 1, 2021 6958
Mechanisms of Trx2/ASK1-Mediated Mitochondrial Injury in Pemphigus Vulgaris. Wei, Bin; Li, Fenghe Report Jan 1, 2021 4186
Upregulation of CDC7 Associated with Cervical Cancer Incidence and Development. Wang, Qingwei; Zheng, Weiping Report Jan 1, 2021 4462
Immune-Related Genes: Potential Regulators and Drug Therapeutic Targets in Hypertrophic Cardiomyopathy. Liu, Wei; Ye, Ju; Cai, Jinqiang; Xie, Feng; Tang, Mengjie; Yang, QinJing Jan 1, 2021 7827
Human Schlafen 5 Inhibits Proliferation and Promotes Apoptosis in Lung Adenocarcinoma via the PTEN/PI3K/AKT/mTOR Pathway. Gu, Xuefeng; Zhou, Li; Chen, Lei; Pan, Huiqing; Zhao, Rui; Guang, Weiwei; Wan, Guoqing Report Jan 1, 2021 6477
Fisetin Attenuates Lipopolysaccharide-Induced Inflammatory Responses in Macrophage. Hada, Yoshiko; Uchida, Haruhito A.; Wada, Jun Report Jan 1, 2021 5362
Understanding the Integrated Pathways and Mechanisms of Transporters, Protein Kinases, and Transcription Factors in Plants under Salt Stress. Shah, Wasifa Hafiz; Rasool, Aadil; Saleem, Seerat; Mushtaq, Naveed Ul; Tahir, Inayatullah; Hakeem, K Jan 1, 2021 13518
IL-6 Promotes the Proliferation and Immunosuppressive Function of Myeloid-Derived Suppressor Cells via the MAPK Signaling Pathway in Bladder Cancer. Zheng, Zhong; Zheng, Xinyi; Zhu, Yiwen; Yao, Zhixian; Zhao, Weiguang; Zhu, Youjia; Sun, Feng Report Jan 1, 2021 6725
Bilobalide Enhances AMPK Activity to Improve Liver Injury and Metabolic Disorders in STZ-Induced Diabetes in Immature Rats via Regulating HMGB1/TLR4/NF-? B Signaling Pathway. Zhao, Meng; Qin, Jianpin; Shen, Wenting; Wu, Aiping Report Jan 1, 2021 6005
Metformin and Fibrosis: A Review of Existing Evidence and Mechanisms. Wu, Maoyan; Xu, Huiwen; Liu, Jingyu; Tan, Xiaozhen; Wan, Shengrong; Guo, Man; Long, Yang Jan 1, 2021 8897
Constitutive Androstane Receptor-Mediated Inhibition of Metformin on Phase II Metabolic Enzyme SULT2A1. Hu, Xiaowen; Li, Mengsiyu; Zhang, Chunxue; Pang, Shuguang Jan 1, 2021 5729
The Polymethoxy Flavonoid Sudachitin Inhibits Interleukin-1? -Induced Inflammatory Mediator Production in Human Periodontal Ligament Cells. Hosokawa, Yoshitaka; Hosokawa, Ikuko; Ozaki, Kazumi; Matsuo, Takashi Report Jan 1, 2021 3137
Metformin-Induced MicroRNA-34a-3p Downregulation Alleviates Senescence in Human Dental Pulp Stem Cells by Targeting CAB39 through the AMPK/mTOR Signaling Pathway. Zhang, Shuo; Zhang, Rong; Qiao, Pengyan; Ma, Xiaocao; Lu, Rongjian; Wang, Feifan; Li, Chuanjie Jan 1, 2021 7291
Proteolytic Processing of CD44 and Its Implications in Cancer. Medrano-González, Priscila Anhel; Rivera-Ramírez, Osmar; Montaño, Luis Felipe; Rendón-Huerta, Erika Jan 1, 2021 10211
Downregulation of microRNA-15b-5p Targeting the Akt3-Mediated GSK-3? /? -Catenin Signaling Pathway Inhibits Cell Apoptosis in Parkinson's Disease. Zhu, Jianzhong; Xu, Xue; Liang, Yingyin; Zhu, Ronglan Report Jan 1, 2021 5998
lncRNA SNHG15 Promotes Ovarian Cancer Progression through Regulated CDK6 via Sponging miR-370-3p. Wang, Yi; Ding, Minghong; Yuan, Xiaoqing; Jiao, Ruibao; Zhu, Dagao; Huang, Wanzhong; Deng, Wenxia Report Jan 1, 2021 3796
mTORC2 Activation Mediated by Mesenchymal Stem Cell-Secreted Hepatocyte Growth Factors for the Recovery of Lipopolysaccharide-Induced Vascular Endothelial Barrier. Meng, Shan-Shan; Guo, Feng-Mei; Huang, Li-Li; Huang, Ying-Zi; Xie, Jian-Feng; Yang, Cong-Shan; Qiu, Jan 1, 2021 5829
Synergistic Antiproliferative Effects of All-Trans Retinoic Acid and Paclitaxel on Autosomal Dominant Polycystic Kidney Disease Epithelial Cells. Nguyen, Que Thanh Thanh; Hoang, Thi Xoan; Ryu, Hyunjin; Oh, Kook-Hwan; Kim, Jae Young Report Jan 1, 2021 6742
Curcumin Improves Epithelial Barrier Integrity of Caco-2 Monolayers by Inhibiting Endoplasmic Reticulum Stress and Subsequent Apoptosis. Zhou, Xinxin; Ren, Mengting; Yang, Jinpu; Pan, Hanghai; Yu, Mosang; Ji, Feng Jan 1, 2021 6376
PDZ Binding Kinase/T-LAK Cell-Derived Protein Kinase Plays an Oncogenic Role and Promotes Immune Escape in Human Tumors. Feng, Tingting; Zhang, Yan; Ling, Sunbin; Xu, Chenyang; Lyu, Yingqi; Lu, Tingting; Liu, Xinyuan Jan 1, 2021 8522
Tomatidine Improves Pulmonary Inflammation in Mice with Acute Lung Injury. Huang, Wen-Chung; Wu, Shu-Ju; Chen, Ya-Ling; Lin, Chwan-Fwu; Liou, Chian-Jiun Jan 1, 2021 4969
Suppression of CHOP Reduces Neuronal Apoptosis and Rescues Cognitive Impairment Induced by Intermittent Hypoxia by Inhibiting Bax and Bak Activation. Xu, Linhao; Bi, Yanli; Xu, Yizhou; Wu, Yihao; Du, Xiaoxue; Mou, Yixuan; Chen, Jian Jan 1, 2021 7352
Exploring the Pharmacological Mechanisms of Tripterygium wilfordii Hook F against Cardiovascular Disease Using Network Pharmacology and Molecular Docking. Huang, Bingwu; Huang, Chengbin; Zhu, Liuyan; Xie, Lina; Wang, Yi; Zhu, Ning Report Jan 1, 2021 6717
Inhibiting PP2Ac? Promotes the Malignant Phenotype of Gastric Cancer Cells through the ATM/METTL3 Axis. Cheng, Zhaoxiang; Gao, Shan; Liang, Xiaojie; Lian, Chao; Chen, Jianquan; Fang, Chao Report Jan 1, 2021 6719
miR-143-3p Inhibits the Differentiation of Osteoclast Induced by Synovial Fibroblast and Monocyte Coculture in Adjuvant-Induced Arthritic Rats. Jiang, Baoping; Yuan, Chengchen; Han, Jing; Shen, Meiyu; Zhou, Xueping; Zhou, Lingling Report Jan 1, 2021 5348
Effects of Ulinastatin on Proliferation and Apoptosis of Breast Cancer Cells by Inhibiting the ERK Signaling Pathway. Xing, Zeyu; Wang, Xin; Liu, Jiaqi; Liu, Gang; Zhang, Menglu; Feng, Kexin; Wang, Xiang Report Jan 1, 2021 3790
Classic and Novel Sex Hormone Binding Globulin Effects on the Cardiovascular System in Men. Basualto-Alarcón, Carla; Llanos, Paola; García-Rivas, Gerardo; Troncoso, Mayarling Francisca; Lagos, Jan 1, 2021 11050
Immunoinformatic Analysis of Calcium-Dependent Protein Kinase 7 (CDPK7) Showed Potential Targets for Toxoplasma gondii Vaccine. Taghipour, Ali; Tavakoli, Sanaz; Sabaghan, Mohamad; Foroutan, Masoud; Majidiani, Hamidreza; Soltani, Report Jan 1, 2021 7143
Tear Film Proteome of Healthy Domestic Cats. Veloso, Jéssica Fontes; Brandão Guedes, Paula Elisa; Lacerda, Luciana Carvalho; Santana, Juliano Oli Jan 1, 2021 8457
Nobiletin Decreases Inflammatory Mediator Expression in Tumor Necrosis Factor-Stimulated Human Periodontal Ligament Cells. Hosokawa, Yoshitaka; Hosokawa, Ikuko; Ozaki, Kazumi Jan 1, 2021 3409
PICK1 Deficiency Exacerbates Sepsis-Associated Acute Kidney Injury. Dou, Qian; Tong, Hang; Yang, Yichun; Zhang, Han; Gan, Hua Report Jan 1, 2021 6017
miR-451 on Myocardial Ischemia-Reperfusion in Rats by Regulating AMPK Signaling Pathway. Guo, Yulin; Gao, Jie; Liu, Yan; Zhang, Xitao; An, Xiangguang; Zhou, Jian; Su, Pixiong Report Jan 1, 2021 7112
Exosomes of Mesenchymal Stem Cells as a Proper Vehicle for Transfecting miR-145 into the Breast Cancer Cell Line and Its Effect on Metastasis. Sheykhhasan, Mohsen; Kalhor, Naser; Sheikholeslami, Azar; Dolati, Masoumeh; Amini, Elaheh; Fazaeli, Report Jan 1, 2021 8801
Exosomes Containing LINC00636 Inhibit MAPK1 through the miR-450a-2-3p Overexpression in Human Pericardial Fluid and Improve Cardiac Fibrosis in Patients with Atrial Fibrillation. Liu, Langsha; Luo, Fanyan; Lei, Kaibo Jan 1, 2021 6085
Human Platelets Take up Anti-VEGF Agents. Sobolewska, B.; Fehrenbacher, B.; Münzer, P.; Kalbacher, H.; Geue, S.; Stellos, Konstantinos; Schall Jan 1, 2021 6294
Key Signaling Pathways Regulate the Development and Survival of Auditory Hair Cells. Liu, Yao; Wei, Mei; Mao, Xiang; Chen, Taisheng; Lin, Peng; Wang, Wei Jan 1, 2021 11046
Overexpression of RIPK4 Predicts Poor Prognosis and Promotes Metastasis in Ovarian Cancer. Liu, Shaoqiu; He, Lewei; Sheng, Chenchen; Su, Rongjia; Wu, Xiaomei; Sun, Yunyan; Xi, Xiaowei Report Jan 1, 2021 4876
Analysis of the Efficacy and Mechanism of Action of Xuebijing Injection on ARDS Using Meta-Analysis and Network Pharmacology. Zhang, Yun; Wang, Jie; Liu, Yong-Mei; Yang, Hui; Wu, Guang-Jun; He, Xuan-Hui Report Jan 1, 2021 6116
Mechanical Stretch Induces Annulus Fibrosus Cell Senescence through Activation of the RhoA/ROCK Pathway. Ning, Li; Gao, Lei; Zhang, Fan; Li, Xiaoxiao; Wang, Tingting Report Jan 1, 2021 3899
A Pan-Cancer Analysis of Clinical Prognosis and Immune Infiltration of CKS1B in Human Tumors. Jia, Yan; Tian, Quan; Yang, Kaitai; Liu, Yi; Liu, Yanfeng Report Jan 1, 2021 7423
Molecular Insights into the MAPK Cascade during Viral Infection: Potential Crosstalk between HCQ and HCQ Analogues. Mohanta, Tapan Kumar; Sharma, Nanaocha; Arina, Pietro; Defilippi, Paola Report Dec 31, 2020 7210
Unravelling Structure, Localization, and Genetic Crosstalk of KLF3 in Human Breast Cancer. Khan, Khushbukhat; Safi, Sadia; Abbas, Asma; Badshah, Yasmin; Dilshad, Erum; Rafiq, Mehak; Zahra, Ka Report Dec 28, 2020 8102
Long Noncoding RNA SNHG12 Promotes Prostate Tumor Occurrence and Progression via AKT Regulation. Chen, Zheng; Qi, Tao; Qin, Xiao-ping; Wang, Jue; Huang, Zhang-sen; Hu, Xiao-yong; Chen, Guo; Qu, Li- Report Dec 22, 2020 5921
Ketamine and Propofol Protect Neuron Cells from Oxygen-Glucose Deprivation-Induced Injury through SAPK/JNK Signalling Pathway. Qi, Aihua; Cao, Yiyun; Wang, Aizhong Report Dec 16, 2020 3589
Inhibition of MEIS3 Generates Cetuximab Resistance through c-Met and Akt. Cai, Ping; Xie, Yangyang; Dong, Mingjun; Zhu, Qiaoqiao Report Dec 9, 2020 5296
10-HDA Induces ROS-Mediated Apoptosis in A549 Human Lung Cancer Cells by Regulating the MAPK, STAT3, NF-? B, and TGF-? 1 Signaling Pathways. Lin, Xin-Mei; Liu, Shao-Bin; Luo, Ying-Hua; Xu, Wan-Ting; Zhang, Yu; Zhang, Tong; Xue, Hui; Zuo, Wen Report Dec 9, 2020 7282
Tangeretin Inhibition of High-Glucose-Induced IL-1ß , IL-6, TGF-ß 1, and VEGF Expression in Human RPE Cells. Qin, Dong; Jiang, Yan-rong Dec 7, 2020 4269
Identification of Differentially Expressed Drought-Responsive Genes in Guar [Cyamopsis tetragonoloba (L.) Taub]. Alshameri, Aref; Al-Qurainy, Fahad; Gaafar, Abdel-Rhman; Khan, Salim; Nadeem, Mohammad; Alansi, Sale Dec 4, 2020 11341
Sex-Based Differences in the Cytokine Production and Intracellular Signaling Pathways in Patients With Rheumatoid Arthritis. Pratap, Uday P.; Hima, Lalgi; Kannan, Thangamani; Thyagarajan, Chadrasekaran; Priyanka, Hannah P.; V Dec 1, 2020 6617
The Effectiveness of Sirolimus Treatment in Two Rare Disorders with Nonketotic Hypoinsulinemic Hypoglycemia: The Role of mTOR Pathway. Siklar, Zeynep; Cetin, Tugba; Cakar, Nilgun; Berberoglu, Merih Clinical report Dec 1, 2020 3107
Dexmedetomidine Protects against Myocardial Ischemia/Reperfusion Injury by Ameliorating Oxidative Stress and Cell Apoptosis through the Trx1-Dependent Akt Pathway. Wu, Zhi-lin; Davis, Jacques Robert Jeppe; Zhu, Yi Report Nov 25, 2020 5036
Deletion of Akt1 Promotes Kidney Fibrosis in a Murine Model of Unilateral Ureteral Obstruction. Kim, Il Young; Lee, Min Young; Park, Mi Wha; Seong, Eun Young; Lee, Dong Won; Lee, Soo Bong; Bae, Su Report Nov 24, 2020 6366
Analysis of Crucial Genes and Pathways Associated with Spared Nerve Injury-Induced Neuropathic Pain. Mao, Dong; Zhai, Huang; Zhao, Gang; Mi, Jingyi; Rui, Yongjun Nov 21, 2020 6228
Mesenchymal Stem Cells Activate the MEK/ERK Signaling Pathway and Enhance DNA Methylation via DNMT1 in PBMC from Systemic Lupus Erythematosus. Xiong, Hui; Guo, Zhixuan; Tang, Zengqi; Ai, Xuechen; Qi, Qing; Liu, Xiuting; Huang, Danqi; Li, Zhaof Report Nov 17, 2020 5006
Role of the AMPK/ACC Signaling Pathway in TRPP2-Mediated Head and Neck Cancer Cell Proliferation. Li, Kun; Chen, Lei; Lin, Zhangying; Zhu, Junwei; Fang, Yang; Du, Juan; Shen, Bing Report Nov 16, 2020 5889
Revealing PAK2's Function in the Cell Division through MKLP1's Interactome. Zhang, Zhao-huan; Liu, Xiu-ling; Zhu, Yun-yi; Huang, Hai; Xu, Xiao-hui Report Nov 6, 2020 4987
RRS1 Promotes Retinoblastoma Cell Proliferation and Invasion via Activating the AKT/mTOR Signaling Pathway. Yan, Xuejing; Wu, Shen; Liu, Qian; Zhang, Jingxue Report Nov 2, 2020 4466
Curcumin Improves the Renal Autophagy in Rat Experimental Membranous Nephropathy via Regulating the PI3K/AKT/mTOR and Nrf2/HO-1 Signaling Pathways. Di Tu, Qiu; Jin, Juan; Hu, Xiao; Ren, Yan; Zhao, Li; He, Qiang Report Nov 2, 2020 6878
Effects of Osthole on Progesterone Secretion in Chicken Preovulatory Follicles Granulosa Cells. Sun, Na; Zhang, Yutong; Hou, Yaxin; Yi, Yanyan; Guo, Jianhua; Zheng, Xiaozhong; Sun, Panpan; Sun, Ya Nov 1, 2020 5077
Monomeric C-reactive protein affects cell injury and apoptosis through activation of p38 mitogen-activated protein kinase in human coronary artery endothelial cells. Zhang, Yong; Cao, Hongxia Report Nov 1, 2020 3987
CDKL2 Is Associated with HER2 Status and Overall Survival in Gastric Cancer: Comparative Analysis of CDKL2 Protein Expression and Gene Copy Number. Shao, Qiong; Wang, Fang; Xu, Yuxia; Zhang, Xu; Tang, Wenting; Feng, Yanfen; Li, Yue Report Oct 31, 2020 6022
Bupleuri Radix Prevents the Recurrences of Resected Colonic Polyps by Affecting Angiogenin-2-Induced Protein Kinase B/Akt Signaling. Gao, Qiang; Yu, Guihong; Yu, Minghui; Wang, Xinping Oct 28, 2020 6135
Gene Expression Profiling of Type 2 Diabetes Mellitus by Bioinformatics Analysis. Zhu, Huijing; Zhu, Xin; Liu, Yuhong; Jiang, Fusong; Chen, Miao; Cheng, Lin; Cheng, Xingbo Oct 23, 2020 4843
The Protective Effect of Qishen Granule on Heart Failure after Myocardial Infarction through Regulation of Calcium Homeostasis. Yang, Xiaomin; Wang, Qiyan; Zeng, Zifan; Zhang, Qian; Liu, Fang; Chang, Hong; Li, Chun Oct 23, 2020 6747
Cardiac CaMKIId and Wenxin Keli Prevents Ang II-Induced Cardiomyocyte Hypertrophy by Modulating CnA-NFATc4 and Inflammatory Signaling Pathways in H9c2 Cells. An, Na; Chen, Yu; Xing, Yanfen; Wu, Honghua; Gao, Xiongyi; Chen, Hengwen; Song, Ke Oct 23, 2020 8653
Melatonin Alleviates Glucose and Lipid Metabolism Disorders in Guinea Pigs Caused by Different Artificial Light Rhythms. Liu, Wei; Zhang, Yunchao; Chen, Qi; Liu, Su; Xu, Weilong; Shang, Wenbin; Wang, Lijuan Oct 23, 2020 8285
KIF3C Promotes Proliferation, Migration, and Invasion of Glioma Cells by Activating the PI3K/AKT Pathway and Inducing EMT. Gao, Yang; Zheng, Hui; Li, Liangdong; Zhou, Changshuai; Chen, Xin; Zhou, Xiaoyan; Cao, Yiqun Report Oct 23, 2020 4550
Trifolium Flavonoids Overcome Gefitinib Resistance of Non-Small-Cell Lung Cancer Cell by Suppressing ERK and STAT3 Signaling Pathways. Wu, Zhiqiang; Xu, Bin; Yu, Zhiyi; He, Qin; Hu, Zhuyuan; Zhou, Shishi; Chen, Meiqin Report Oct 23, 2020 3841
Association of Glycemic Indices (Hyperglycemia, Glucose Variability, and Hypoglycemia) with Oxidative Stress and Diabetic Complications. Papachristoforou, Eleftheria; Lambadiari, Vaia; Maratou, Eirini; Makrilakis, Konstantinos Oct 16, 2020 19469
Luteolin Attenuates IL-1ß -Induced THP-1 Adhesion to ARPE-19 Cells via Suppression of NF-? B and MAPK Pathways. Huang, Wen-Chung; Liou, Chian-Jiun; Shen, Szu-Chuan; Hu, Sindy; Hsiao, Chien-Yu; Wu, Shu-Ju Oct 16, 2020 6779
Protective Effects of Adiponectin against Cobalt Chloride-Induced Apoptosis of Smooth Muscle Cells via cAMP/PKA Pathway. Xiao, Jingjie; Zhang, Yingying; Zhang, Wei; Zhang, Liang; Li, Li; Si, Junqiang; Li, Xinzhi; Ma, Keta Report Oct 12, 2020 5421
Guttiferone K Exerts the Anti-inflammatory Effect on Mycobacterium Tuberculosis- (H37Ra-) Infected Macrophages by Targeting the TLR/IRAK-1 Mediated Akt and NF-? B Pathway. Zhang, Qingwen; Sun, Jinxia; Fu, Yan; He, Weigang; Li, Yinhong; Tan, Hongsheng; Xu, Hongxi Oct 10, 2020 7913
Tilianin Protects against Ischemia/Reperfusion-Induced Myocardial Injury through the Inhibition of the Ca[sup.2+]/Calmodulin-Dependent Protein Kinase II-Dependent Apoptotic and Inflammatory Signaling Pathways. Jiang, Hailun; Xing, Jianguo; Fang, Jiansong; Wang, Linlin; Wang, Yu; Zeng, Li; Li, Zhuorong Report Oct 9, 2020 9213
MicroRNA-31-5p Exacerbates Lipopolysaccharide-Induced Acute Lung Injury via Inactivating Cab39/AMPKa Pathway. Jiang, Wan-li; Zhao, Kao-chang; Yuan, Wen; Zhou, Fang; Song, Heng-ya; Liu, Gao-li; Huang, Jie Oct 8, 2020 8158
Effects of Single-Nucleotide Polymorphisms in Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2): A Comprehensive Study. Khalid, Zoya; Almaghrabi, Omar Oct 6, 2020 5349
Lack of PPAR? /? -Inactivated SGK-1 Is Implicated in Liver Carcinogenesis. Shen, Bo; Li, Aimin; Wan, Yu-Jui Yvonne; Shen, Guijia; Zhu, Jinshui; Nie, Yuqiang Report Oct 5, 2020 5878
Wubeizi Ointment Suppresses Keloid Formation through Modulation of the mTOR Pathway. Tang, Zhiming; Cao, Yi; Ding, Jicun; Zhai, Xiaoxiang; Jing, Mengqing; Wang, Mengmeng; Lu, Lu Report Sep 30, 2020 5758
Isokotomolide A from Cinnamomum kotoense Induce Melanoma Autophagy and Apoptosis In Vivo and In Vitro. Li, Jian; Chen, Chung-Yi; Huang, Jyun Yin; Wang, Lin; Xu, Zixuan; Kang, Wenyi; Lin, Miao-Hsia Sep 27, 2020 8970
EEF1D Promotes Glioma Proliferation, Migration, and Invasion through EMT and PI3K/Akt Pathway. Xie, Cheng; Zhou, Mingfeng; Lin, Jie; Wu, Zhiyong; Ding, Shengfeng; Luo, Jie; Zhan, Zhengming; Song, Report Sep 25, 2020 5624
USP46 Inhibits Cell Proliferation in Lung Cancer through PHLPP1/AKT Pathway. Wang, Wei; Chen, Meng; Xu, Hailing; Lv, Dongqing; Zhou, Suna; Yang, Haihua Report Sep 24, 2020 4838
Berberine Attenuates Cerebral Vasospasm After Experimental Subarachnoid Hemorrhage Via Modulating AMPK/Rho Pathway. Kadirhan, Ozge Altintas; Kumas, Meltem; Karatas, Ersin; Mutlu, Hasan Serdar; Kocyigit, Abdurrahim; A Sep 1, 2020 4478
The Relationship Between Serum Angiogenic Factor Levels and Disease Activity in Rheumatoid Arthritis. Aslanalp, Zahide; Tikiz, Canan; Ulusoy, Aslihan; Orguc, Sebnem; Yedekci, Aysun BILGI; Ulman, Cevval Sep 1, 2020 5792
Cardiac Transcriptomics Reveals That MAPK Pathway Plays an Important Role in Hypoxia Tolerance in Bighead Carp (Hypophthalmichthys nobilis). Zhou, Ying; Luo, Weiwei; Yu, Xiaomu; Wang, Junru; Feng, Yizhao; Tong, Jingou Report Sep 1, 2020 6958
Fermented Feed Modulates Meat Quality and Promotes the Growth of Longissimus Thoracis of Late-Finishing Pigs. Qiu, Yueqin; Li, Kebiao; Zhao, Xichen; Liu, Shilong; Wang, Li; Yang, Xuefen; Jiang, Zongyong Report Sep 1, 2020 9496
Function of Dicer with regard to Energy Homeostasis Regulation, Structural Modification, and Cellular Distribution. Tong, Xiaohui; Yu, Nianjun; Han, Rongchun; Wang, Tongsheng Aug 31, 2020 5395
Polymorphonuclear Cell Chemotaxis and Suicidal NETosis: Simultaneous Observation Using fMLP, PMA, H7, and Live Cell Imaging. Pai, Delou; Gruber, Michael; Pfaehler, Sophie-Marie; Bredthauer, Andre; Lehle, Karla; Trabold, Bened Aug 31, 2020 6299
Oxidized Oils and Oxidized Proteins Induce Apoptosis in Granulosa Cells by Increasing Oxidative Stress in Ovaries of Laying Hens. Zhou, Ling; Ding, Xuemei; Wang, Jianping; Bai, Shiping; Zeng, Qiufeng; Su, Zuowei; Xuan, Yue; Wu, Ai Aug 31, 2020 7230
Mechanisms of the Regulation and Dysregulation of Glucagon Secretion. Onyango, Arnold N. Aug 31, 2020 6785
Silencing ARAF Suppresses the Malignant Phenotypes of Gallbladder Cancer Cells. Lin, Weiguo; Tong, Chenhao; Zhang, Weiguang; Cen, Wenda; Wang, Yali; Li, Jiandong; Zhu, Zhiyang; Yu, Report Aug 31, 2020 3866
Phloretin Modulates Human Th17/Treg Cell Differentiation In Vitro via AMPK Signaling. Jiao, Ao; Yang, Zhaoming; Fu, Xibo; Hua, Xiangdong Aug 31, 2020 4885
Identification and Characterization of MAPK Signaling Pathway Genes and Associated lncRNAs in the Ileum of Piglets Infected by Clostridium perfringens Type C. Luo, Ruirui; Huang, Xiaoyu; Yan, Zunqiang; Gao, Xiaoli; Wang, Pengfei; Yang, Qiaoli; Wang, Wei; Xie, Report Aug 31, 2020 6768
CLEC3B protects H9c2 cardiomyocytes from apoptosis caused by hypoxia via the PI3K/Akt pathway. Lv, Fenghua; Wang, Zhuo; Huang, Yanli; Si, Aoyang; Chen, Yulei Aug 26, 2020 4003
Characterization of microRNAs during Embryonic Skeletal Muscle Development in the Shan Ma Duck. Li, Chuan; Xiong, Ting; Zhou, Mingfang; Wan, Lei; Xi, Suwang; Liu, Qiuhong; Chen, Yi; Mao, Huirong; Aug 1, 2020 7922
Inhibitory effect of microRNA-608 on lung cancer cell proliferation, migration, and invasion by targeting BRD4 through the JAK2/STAT3 pathway. Xu, Weigang; Sun, Dapeng; Wang, Yanqin; Zheng, Xinlin; Li, Yan; Xia, Yu; Teng, Yanan Report Aug 1, 2020 5514
Astragalus membranaceus Injection Suppresses Production of Interleukin-6 by Activating Autophagy through the AMPK-mTOR Pathway in Lipopolysaccharide-Stimulated Macrophages. Zhang, Xiaoyan; Liang, Taigang; Yang, Wanxia; Zhang, Lanfang; Wu, Shuting; Yan, Chaoqun; Li, Qingsha Jul 31, 2020 10297
Mitogen- and Stress-Activated Protein Kinase 1 Mediates Alcohol-Upregulated Transcription of Brf1 and tRNA Genes to Cause Phenotypic Alteration. Lin, Mingen; Huang, Chenghao; Ren, Wenfeng; Chen, Jun; Xia, Ningshao; Zhong, Shuping Jul 31, 2020 6745
Identification of Potential Inhibitors of Calcium/Calmodulin-Dependent Protein Kinase IV from Bioactive Phytoconstituents. Gupta, Preeti; Khan, Shama; Fakhar, Zeynab; Hussain, Afzal; Rehman, Tabish; AlAjmi, Mohamed F.; Isla Jul 31, 2020 8775
Corrigendum to "Activation of AMP-Activated Protein Kinase and Extracelluar Signal-Regulated Kinase Mediates CB-PIC-Induced Apoptosis in Hypoxic SW620 Colorectal Cancer Cells". Cho, Sung-Yun; Lee, Hyo-Jeong; Lee, Hyo-Jung; Jung, Deok-Beom; Kim, Hyunseok; Sohn, Eun Jung; Kim, B Correction notice Jul 31, 2020 618
Polygonum multiflorum Thunb. Extract Stimulates Melanogenesis by Induction of COX2 Expression through the Activation of p38 MAPK in B16F10 Mouse Melanoma Cells. Kim, Donghee; Kim, Hyo-Jin; Ju, Hee-Sook Jul 31, 2020 6759
The Study of the Response of Fat Metabolism to Long-Term Energy Stress Based on Serum, Fatty Acid and Transcriptome Profiles in Yaks. Xiong, Lin; Pei, Jie; Wu, Xiaoyun; Kalwar, Qudratullah; Liang, Chunnian; Guo, ian; Chu, Min; Bao, Pe Report Jul 1, 2020 9876
Genome-Wide Identification and Expression Analysis of MAPK and MAPKK Gene Family in Pomegranate (Punica Granatum L.). Ren, Yuan; Ge, Dapeng; Dong, Jianmei; Guo, Linhui; Yuan, Zhaohe Jul 1, 2020 7487
Prospecting for Breast Cancer Blood Biomarkers: DeathAssociated Protein Kinase 1 (DAPK1) as a Potential Candidate. Arko-Boham, Benjamin; Owusu, Bright Afriyie; Aryee, Nii Ayite; Blay, Richard Michael; Owusu, Ewurama Jun 30, 2020 4686
Adaptive Molecular Evolution of AKT3 Gene for Positive Diversifying Selection in Mammals. Farmanullah; Hosseini, Seyed Mahdi; Liang, Aixin; Hua, Guohua; ur Rehman, Zia; Talpur, Hira Sajjad; Jun 30, 2020 7244
Inhibition of eIF2[alpha] Dephosphorylation Protects Hepatocytes from Apoptosis by Alleviating ER Stress in Acute Liver Injury. Tang, Yong-Jing; Chen, Huan; Yi, Yu; Chen, Gui-Mei; Yang, Fang-Wan; Li, Ying; Tian, Ren-Dong; Huang, Jun 30, 2020 5820
Crocin Improves Insulin Sensitivity and Ameliorates Adiposity by Regulating AMPK-CDK5-PPAR/ Signaling. Fang, Kai; Gu, Ming Jun 30, 2020 3925
Wenxin Granule Ameliorates Hypoxia/Reoxygenation-Induced Oxidative Stress in Mitochondria via the PKC-[delta]/NOX2/ROS Pathway in H9c2 Cells. Jin, Qihui; Jiang, Yanhong; Fu, Lizhong; Zheng, Yanqiu; Ding, Yuxia; Liu, Qian Jun 30, 2020 8003
Autophagy Functions to Prevent Methylglyoxal-Induced Apoptosis in HK-2 Cells. Park, So-Hyun; Choi, Hyun-Il; Ahn, Jiyun; Jang, Young-Jin; Ha, Tae-Youl; Seo, Hyo-Deok; Kim, Yoon-So Jun 30, 2020 5288
Cyclin-Dependent Kinase-Like 5 (CDKL5): Possible Cellular Signalling Targets and Involvement in CDKL5 Deficiency Disorder. Katayama, Syouichi; Sueyoshi, Noriyuki; Inazu, Tetsuya; Kameshita, Isamu Jun 30, 2020 10057
Protein Level and Infantile Diarrhea in a Postweaning Piglet Model. Gao, Jing; Yin, Jie; Xu, Kang; Han, Hui; Liu, Ze Min; Wang, Chen Yu; Li, Tie Jun; Yin, Yu Long Jun 30, 2020 8553
Single Nucleotide Polymorphisms in CDKAL1 Gene are not Associated with Risk of Type 2 Diabetes Mellitus in a Group of Egyptian Population. Darwish, Rania; Abdel-Hamid, Eman; Gohar, Nadida; Soliman, Ahmed; Naguib, Mervat Report Jun 1, 2020 4342
Bone marrow mesenchymal stem cells differentiate into intestinal epithelioid cells through the ERK1/2 pathway. Jiang, Ting; Shi, Meng-lin; Xia, Geng; Yang, Yi-na; Xu, Jia-min; Lei, Yun-jie; Tang, Ying-mei; Yang, Jun 1, 2020 3726
Bone marrow mesenchymal stem cells differentiate into intestinal epithelioid cells through the ERK1/2 pathway. Jiang, Ting; Shi, Meng-Lin; Xia, Geng; Yang, Yi-Na; Xu, Jia-Min; Lei, Yun-Jie; Tang, Ying-Mei; Yang, Jun 1, 2020 3554
Apoptosis Signaling Pathway Regulates the Gene Expression in the Yeast Retrotransposons Ty1 and Ty2. Colakoglu, Ceyda; Turkel, Sezai Jun 1, 2020 5149
Vanillic Acid Alleviates Acute Myocardial Hypoxia/Reoxygenation Injury by Inhibiting Oxidative Stress. Yao, Xiuya; Jiao, Shoufeng; Qin, Mingming; Hu, Wenfeng; Yi, Bo; Liu, Dan May 31, 2020 6124
Mechanisms of Cong Rong Shu Jing Compound Effects on Endoplasmic Reticulum Stress in a Rat Model of Parkinson's Disease. Lin, Yao; Tang, Lanfang; Huang, Peizhen; Liu, Ting; Zhong, Jianan; Xu, Qian; Li, Xiyu; Lin, Youning; May 31, 2020 5428
Antiprolactinoma Effect of Hordenine by Inhibiting MAPK Signaling Pathway Activation in Rats. Wang, Xiong; Guo, Run-zhu; Ma, Li; Ding, Qiao-yan; Meng, Jun-hua; Chen, Yong- gang; Wu, Jin-hu May 31, 2020 3801
Activation of Inward Rectifier [K.sup.+] Channel 2.1 by PDGF-BB in Rat Vascular Smooth Muscle Cells through Protein Kinase A. Tang, Chengchun; Wang, Dong; Luo, Erfei; Yan, Gaoliang; Liu, Bo; Hou, Jiantong; Qiao, Yong May 31, 2020 5152
Catalpol Attenuates Hepatic Steatosis by Regulating Lipid Metabolism via AMP-Activated Protein Kinase Activation. Tian, Xiang; Ru, Qin; Xiong, Qi; Wen, Ruojian; Chen, Yong May 31, 2020 6095
Integrated Bioinformatics Analysis of the Clinical Value and Biological Function of ATAD2 in Hepatocellular Carcinoma. Meng, Xiangyu; Wang, Lu; Zhu, Bo; Zhang, Jun; Guo, Shuai; Li, Qiang; Zhang, Tao; Zheng, Zhichao; Wu, May 31, 2020 10086
New Synthetic 3-Benzoyl-5-Hydroxy-2H-Chromen-2-One (LM-031) Inhibits Polyglutamine Aggregation and Promotes Neurite Outgrowth through Enhancement of CREB, NRF2, and Reduction of AMPK[alpha] in SCA17 Cell Models. Chen, Chiung-Mei; Chen, Wan-Ling; Yang, Shu-Ting; Lin, Te-Hsien; Yang, Shu-Mei; Lin, Wenwei; Chao, C Report May 31, 2020 10064
Differential expression of DNA-dependent protein kinase catalytic subunit in the brain of neonatal mice and young adult mice. Okawa, Aoi; Morioka, Takamitsu; Imaoka, Tatsuhiko; Kakinuma, Shizuko; Matsumoto, Yoshihisa Report May 1, 2020 5473
Protein Kinase A Is Involved in Neuropathic Pain by Activating the p38MAPK Pathway to Mediate Spinal Cord Cell Apoptosis. Deng, Yajun; Yang, Liang; Xie, Qiqi; Yang, Fengbiao; Li, Guoqiang; Zhang, Guangzhi; Li, Shaoping; Wu Apr 30, 2020 7235
Anti-Inflammatory Profile of Jungia sellowii Less. by Downregulation of Proinflammatory Mediators and Inhibition of NF-[kappa]B and p38 Pathways. Vicente, Geison; Moon, Yeo Jim Kinoshita; Rosa, Daniela Weingartner; Lima, Luise Azevedo; Saleh, Naj Apr 30, 2020 9663
Sinapic Acid Promotes Browning of 3T3-L1 Adipocytes via p38 MAPK/CREB Pathway. Bae, In-Seon; Kim, Sang Hoon Apr 30, 2020 4197
SAD-B modulates epileptic seizure by regulating AMPA receptors in patients with temporal lobe epilepsy and in the PTZ-induced epileptic model. Li, Rong; He, Miaoqing; Wu, Bing; Zhang, Peng; Zhang, Qinbin; Chen, Yangmei Apr 1, 2020 5577
Chromium acetate stimulates adipogenesis through regulation of gene expression and phosphorylation of adenosine monophosphate-activated protein kinase in bovine intramuscular or subcutaneous adipocytes. Kim, Jongkyoo; Chung, Kiyong; Johnson, Bradley J. Apr 1, 2020 4958
Identification of Three lncRNAs as Potential Predictive Biomarkers of Lung Adenocarcinoma. Jin, Donghui; Song, Yuxuan; Chen, Yuan; Zhang, Peng Mar 31, 2020 5270
The Roles of AMPK in Revascularization. Chen, Ming-Hong; Fu, Qiong-Mei Mar 31, 2020 8884
Islet Stellate Cells Regulate Insulin Secretion via Wnt5a in Min6 Cells. Xu, Wei; Jones, Peter M.; Geng, Houfa; Li, Rui; Liu, Xuekui; Li, Yinxia; Lv, Qian; Liu, Ying; Wang, Mar 31, 2020 6596
Oridonin Attenuates Lipopolysaccharide-Induced ROS Accumulation and Inflammation in HK-2 Cells. Huang, Jen-Hsuan; Lan, Chou-Chin; Hsu, Ya-Ting; Tsai, Cheng-Lin; Tzeng, I-Shiang; Wang, Po; Kuo, Cha Mar 31, 2020 4812
Improving Small Intestinal Motility in Experimental Acute Necrotising Pancreatitis by Modulating the CPI-17/MLCP Pathway Using Chaiqin Chengqi Decoction. Lin, Ziqi; Zhang, Chenlong; Zhang, Xiaoxin; Shi, Na; Wen, Yongjian; Han, Chengxia; Du, Dan; Liu, Tin Mar 1, 2020 8169
Activation of the NF-[kappa]B and MAPK Signaling Pathways Contributes to the Inflammatory Responses, but Not Cell Injury, in IPEC-1 Cells Challenged with Hydrogen Peroxide. Xiao, Kan; Liu, Congcong; Tu, Zhixiao; Xu, Qiao; Chen, Shaokui; Zhang, Yang; Wang, Xiuying; Zhang, J Mar 1, 2020 8713
Autophagy Triggered by Oxidative Stress Appears to Be Mediated by the AKT/mTOR Signaling Pathway in the Liver of Sleep-Deprived Rats. Li, Yongmei; Zhang, Yuan; Ji, Guang; Shen, Yiwei; Zhao, Nan; Liang, Yuhan; Wang, Zihan; Liu, Mengqi; Mar 1, 2020 5705
Hydrogen Gas Attenuates Hypoxic-Ischemic Brain Injury via Regulation of the MAPK/HO-1/PGC-1a Pathway in Neonatal Rats. Wang, Peipei; Zhao, Mingyi; Chen, Zhiheng; Wu, Guojiao; Fujino, Masayuki; Zhang, Chen; Zhou, Wenjuan Mar 1, 2020 8350
Cordyceps cicadae Mycelia Ameliorate Cisplatin-Induced Acute Kidney Injury by Suppressing the TLR4/NF-[kappa]B/MAPK and Activating the HO-1/Nrf2 and Sirt-1/AMPK Pathways in Mice. Deng, Jeng-Shyan; Jiang, Wen-Ping; Chen, Chin-Chu; Lee, Li-Ya; Li, Pei-Ying; Huang, Wen-Chin; Liao, Mar 1, 2020 8923
Exploring the Key Genes and Pathways in the Formation of Corneal Scar Using Bioinformatics Analysis. Liu, Binfeng; Li, Ang; Wang, Hongbo; Wang, Jialin; Zhai, Gongwei; Ma, Haohao; Feng, Shiqing; Liu, Li Mar 1, 2020 6357
Resveratrol's Impact on Vascular Smooth Muscle Cells Hyporeactivity: The Role of Rho-Kinase Inhibition. Wicinski, Michal; Malinowski, Bartosz; Rajewski, Pawel; Szychta, Pawel; Wodkiewicz, Eryk; Walczak, M Mar 1, 2020 6288
Systemic Administration of Calea pinnatifida Inhibits Inflammation Induced by Carrageenan in a Murine Model of Pulmonary Neutrophilia. Facchin, Bruno Matheus de Campos; da Rosa, Julia Salvan; Luz, Ana Beatriz Gobbo; Moon, Yeo Jim Kinos Mar 1, 2020 10433
Exendin-4 Improves Diabetic Kidney Disease in C57BL/6 Mice Independent of Brown Adipose Tissue Activation. Fang, Shu; Cai, Yingying; Lyu, Fuping; Zhang, Hongbin; Wu, Chunyan; Zeng, Yanmei; Fan, Cunxia; Zou, Mar 1, 2020 4931
Dysregulation in the Unfolded Protein Response in the FGR Rat Pancreas. Liu, Xiaomei; Guo, Yanyan; Wang, Jun; Zhu, Liangliang; Gao, Linlin Mar 1, 2020 5642
Comparative Inotropic Effects of the Some Isoquinoline Alkaloids. Jumayev, Inoyat; Usmanov, Pulat; Rustamov, Shavkat; Zhurakulov, Sherzod Report Mar 1, 2020 4100
Study of the AMP-activated Protein Kinase Role in Energy Metabolism Changes during the Postmortem Aging of Yak Longissimus dorsal. Yang, Yayuan; Han, Ling; Yu, Qunli; Gao, Yongfang; Song, Rende Report Mar 1, 2020 7426
The Expression of ERK1/2 in Female Yak (Bos grunniens) Reproductive Organs. Fan, Jiangfeng; Han, Xiaohong; He, Honghong; Luo, Yuzhu; Yu, Sijiu; Cui, Yan; Xu, Gengquan; Wang, Li Report Feb 1, 2020 8177
Integrin beta 4 (ITGB4) and its tyrosine-1510 phosphorylation promote pancreatic tumorigenesis and regulate the MEK1-ERK 1/2 signaling pathway. Meng, Xiangli; Liu, Peng; Wu, Yunhao; Liu, Xinlu; Huang, Yinpeng; Yu, Boqiang; Han, Jiahong; Jin, Ha Report Feb 1, 2020 6617
Pipeline Review of RAC Beta Serine/Threonine Protein Kinase - H1, 2020. Jan 28, 2020 1154
Protein Kinase C Theta Type, Pipeline Review, H1 2020: Stage of Development, Mechanism of Action, Route of Administration & Molecule Type. Jan 27, 2020 1073
Tyrosine Protein Kinase Fyn - Pipeline Review, H1 2020. Jan 24, 2020 1191
Mitogen Activated Protein Kinase 1, Pipeline Review, H2 2019 - Antengene Corp, Kura Oncology Inc & Kalyra Pharmaceuticals Inc. Jan 16, 2020 1244
Cyclin Dependent Kinase 6 - Pipeline Review, H2 2019. Jan 16, 2020 1164
Aurora Kinase A, Pipeline Review, H2 2019 - AbbVie Inc, Cielo Therapeutics Inc & Taiho Pharmaceutical Co Ltd. Jan 16, 2020 1105
Serine Threonine Protein Kinase Pim 1 - Pipeline Review, H2 2019. Jan 15, 2020 1032
Serine Threonine Protein Kinase Pim 3, Pipeline Review, H2 2019 - Incyte Corp, Jasco Pharmaceuticals, Novartic AG & Yakult Honsha Co. Ltd. Jan 15, 2020 1097
RAC Gamma Serine Threonine Protein Kinase - Pipeline Review, H2 2019. Jan 15, 2020 1249
Serine Threonine Protein Kinase Pim 2, Pipeline Review, H2 2019: Amgen Inc, Inflection Biosciences Ltd & Zovis Pharmaceuticals. Jan 15, 2020 1061
Serine Threonine Protein Kinase PLK1, Pipeline Review, H2 2019 - Leukemia, Breast Cancer, Hodgkin Lymphona & Rhabdomyosarcoma. Jan 15, 2020 1204
RAC Alpha Serine Threonine Protein Kinase - Pipeline Review, H2 2019. Jan 15, 2020 1278
Serine Threonine Protein Kinase ATR, Pipeline Review, H2 2019 - Artios Pharma Ltd, Bayer AG, IMPACT Therapeutics Inc & Pfizer Inc. Jan 15, 2020 1187
Cell Division Cycle 7 Related Protein Kinase, Pipeline Review, H2 2019 - Lin Bioscience Inc, NMS Group SpA & Sierra Oncology Inc. Jan 14, 2020 1041
Leucine Rich Repeat Serine Threonine Protein Kinase 2, Pipeline Review, H2 2019 - Central Nervous System, Cardiovascular, Oncology & Ophthalmology. Jan 14, 2020 1016
Melanogenic Effects of Maclurin Are Mediated through the Activation of cAMP/PKA/CREB and p38 MAPK/CREB Signaling Pathways. Hwang, Young Sun; Oh, Sae Woong; Park, See-Hyoung; Lee, Jienny; Yoo, Ju Ah.; Kwon, Kitae; Park, Se J Jan 1, 2020 5203
Next-Generation Sequencing Panel Analysis of Clinically Relevant Mutations in Circulating Cell-Free DNA from Patients with Gestational Trophoblastic Neoplasia: A Pilot Study. Luo, Lingxiao; Lin, Ling; Zhang, Xiaoyan; Cai, Qingqing; Zhao, Hongbo; Xu, Congjian; Cong, Qing Report Jan 1, 2020 4380
Total Panax notoginseng saponin inhibits balloon injury-induced neointimal hyperplasia in rat carotid artery models by suppressing pERK/p38 MAPK pathways. Yang, Zheng; Zhang, Hui; An, Ming; Bian, Mengni; Song, Miao; Guo, Xiaohua; Liu, Quanli; Qiu, Min Report Jan 1, 2020 5827
Overcoming Resistance to Therapies Targeting the MAPK Pathway in BRAF-Mutated Tumours. Paton, Emily L.; Turner, Jacqueline A.; Schlaepfer, Isabel R. Jan 1, 2020 11230
Bu Shen Zhu Yun Decoction Improves Endometrial Receptivity via VEGFR-2-Mediated Angiogenesis. Li, Li; Jiang, Huabo; Wei, Xuecong; Geng, Dandan; He, Ming; Du, Huilan Jan 1, 2020 6404
Molecular Insights into the MAPK Cascade during Viral Infection: Potential Crosstalk between HCQ and HCQ Analogues. Mohanta, Tapan Kumar; Sharma, Nanaocha; Arina, Pietro; Defilippi, Paola Report Jan 1, 2020 7210
Electroacupuncture Attenuates CFA-Induced Inflammatory Pain by Regulating CaMKII. Gu, Yixiao; Chen, Shuangdong; Mo, Yunchang; Tu, Yingying; Chen, Na; Zhao, Xiaoyong; Li, Shan Jan 1, 2020 5949
Lipid Catabolism in Starved Yak Is Inhibited by Intravenous Infusion of [beta]-Hydroxybutyrate. Zou, Huawei; Hu, Rui; Dong, Xianwen; Shah, Ali Mujtaba; Wang, Zhisheng; Ma, Jian; Peng, Quanhui; Xue Report Jan 1, 2020 9953
Inhibitor 1 of Protein Phosphatase 1 Regulates [Ca.sup.2+]/Calmodulin-Dependent Protein Kinase II to Alleviate Oxidative Stress in Hypoxia-Reoxygenation Injury of Cardiomyocytes. Luo, Huiqin; Song, Shu; Chen, Yun; Xu, Mengting; Sun, Linlin; Meng, Guoliang; Zhang, Wei Dec 31, 2019 8381
Simvastatin Mitigates Apoptosis and Transforming Growth Factor-Beta Upregulation in Stretch-Induced Endothelial Cells. Dong, Gang; Huang, Xiaoquan; Jiang, Siyu; Ni, Liyuan; Chen, Shiyao Dec 31, 2019 4879
Effects of Angiotensin-(1-7) and Angiotensin II on Acetylcholine-Induced Vascular Relaxation in Spontaneously Hypertensive Rats. Zhang, Feng; Xu, Yu; Pan, Yan; Sun, Shuo; Chen, Aidong; Li, Peng; Bao, Changlei; Wang, Jian; Tang, H Dec 31, 2019 6966
Sesamin, a Naturally Occurring Lignan, Inhibits Ligand-Induced Lipogenesis through Interaction with Liver X Receptor Alpha (LXR[alpha]) and Pregnane X Receptor (PXR). Tai, Tsai-Sung; Tien, Ni; Shen, Hsin-Yi; Chu, Fang-Yi; Wang, Charles C.N.; Lu, Chieh-Hsiang; Yu, Hui Dec 31, 2019 10200
Structure and function of the insulin receptor--a personal perspective. Kasuga, Masato Dec 1, 2019 5419
Protective Role of mTOR in Liver Ischemia/Reperfusion Injury: Involvement of Inflammation and Autophagy. Zhang, Tao; Guo, Jianrong; Gu, Jian; Chen, Ke; Li, Huili; Wang, Jiliang Nov 30, 2019 12695
Inhibition of cAMP/PKA Pathway Protects Optic Nerve Head Astrocytes against Oxidative Stress by Akt/Bax Phosphorylation-Mediated Mfn1/2 Oligomerization. Ju, Won-Kyu; Shim, Myoung Sup; Kim, Keun-Young; Park, Tae Lim; Ahn, Sangphil; Edwards, Genea; Weinre Nov 30, 2019 9810
Urinary Metabolomics Study of the Intervention Effect of Hypoglycemic Decoction on Type 2 Diabetes Mellitus Rats Model. Pan, Lin-Lin; Sun, Qi-Hui; Liu, Gui-Rong; Guo, Jia-Yin Report Nov 30, 2019 7913
Thrombin Induces Secretion of Multiple Cytokines and Expression of Protease-Activated Receptors in Mouse Mast Cell Line. Fang, Xiaobin; Liao, Ren; Yu, Yingyan; Li, Jingyi; Guo, Zaipei; Zhu, Tao Nov 30, 2019 6479
Iguratimod Inhibits the Aggressiveness of Rheumatoid Fibroblast-Like Synoviocytes. Lin, Jin; Yu, Ye; Wang, Xuanwei; Ke, Yini; Sun, Chuanyin; Yue, Lihuan; Xu, Guanhua; Xu, Bei; Xu, Liq Nov 30, 2019 5542
Adipokine Chemerin Stimulates Progression of Atherosclerosis in [ApoE.sup.-/-] Mice. Liu, Huadong; Xiong, Wei; Luo, Yu; Chen, Hua; He, Yaqiong; Cao, Yuanzhi; Dong, Shaohong Nov 30, 2019 4552
Palmitic Acid Induces MicroRNA-221 Expression to Decrease Glucose Uptake in HepG2 Cells via the PI3K/AKT/GLUT4 Pathway. Huang, Fang; Chen, Jie; Wang, Jingwen; Zhu, Pingping; Lin, Wenting Nov 30, 2019 4077

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