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Principles of asymmetric synthesis, 2d ed.


Principles of asymmetric synthesis, 2d ed.

Gawley, Robert E. and Jeffrey Aube.



555 pages



Retaining the format of the 1996 first edition, Gawley (chemistry and biochemistry, U. of Arkansas) and Aube (medicinal chemistry U. of Kansas-Lawrence) select several reaction categories that comprise many of the most useful synthetic reactions types. Their focus is on the principles that govern relative and absolute configurations in transition state assemblies. After a general introduction and glossary, they cover practical aspects of asymmetric synthesis; enolate azaenolate, and organolithium alkylations; 1,2-additions and 1,4-additions to C=X bonds; aldol and Micheal additions of allyls, enolates, and enolate equivalents; cycloadditions and rearrangements; reductions and hydroborations, and oxidations.

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Publication:Reference & Research Book News
Article Type:Book review
Date:Jun 1, 2013
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