Printer Friendly

Prenatal smoking exposure disrupts sleep patterns in preemies.

Byline: ANI

Washington, Dec 1 (ANI): In a first of its kind study, scientists have shown that high levels of prenatal smoking exposure strongly modify sleep patterns in premature babies, which may have serious consequences for the development of the infant's brain

According to the results, preterm neonates born to heavy-smoking mothers who smoked more than 10 cigarettes per day lead to disrupted sleep structure and sleep continuity-from 7 p.m. to 8 a.m. they slept almost two hours less than controls who were born to non-smoking mothers, and their sleep was more fragmented.

As compared with controls, neonates born to both heavy and low smokers displayed more body movements and, as a result, more disturbed sleep.

Frederic Telliez, principal investigator, and professor of neuroscience at the University of Picardie Jules Verne in Amiens, France said that sleep integrity is critical in the brain development of neonates.

Also, he said that the disruption of sleep mechanisms by prenatal smoking exposure may predispose neonates to alterations in some physiological function (such as ventilation) and can result in long-term neurocognitive disorders.

The authors said that abnormal sleep processes might alter compensatory responses to autonomic cardiovascular/respiratory challenge and increase the likelihood of life-threatening events later in life.

Prenatal smoking exposure can lead to deficits in sustained attention and impulsivity in adolescence and a higher risk of attention-deficit/hyperactivity disorder in childhood.

Such effects could be partially mediated by sleep changes. Prenatal smoking exposure is also highly related to sudden infant death syndrome (SIDS).

"The developing brain is known for its plasticity and ability to reorganize in response to the stimulation provided by the postnatal environment," said Telliez.

He added: "Consequently, it is possible that these neonates, if they are not exposed to smoking after birth, could recover and develop normal sleep structures."

For the study, the researchers recruited 40 healthy preterm neonates (postconceptional age approximately 33.9 weeks) from the neonatal intensive care unit at Amiens University Medical Center in France.

It was found that the neonates born to heavy-smoking mothers had a significantly lower mean birth weight than controls. Their average weight of 2.92 pounds was 21 percent less than the average weight of controls, which was 3.69 pounds.

Neonates born to mothers who smoked less than 10 cigarettes per day had a birth weight that was 11 percent lower than controls, although this result did not achieve statistical significance.

The study also found that even after 29.7 days without postnatal exposure to smoking or nicotine, and despite the fact that neonates in the heavy-smoking group were nearly 10 days older, infants exposed in utero to high levels of smoking still showed an altered organization of the various behavioural states.

The researchers said that examining the neurodevelopmental trajectories of neonates exposed to maternal smoking (and of those who were not) could lead to greater understanding of potential deficits in the exposed group, better prediction of outcomes, and potentially more effective compensatory clinical interventions.

Researchers also stated that longitudinal studies are necessary to assess the persistence of behavioural state effects caused by prenatal smoking exposure.

The study is published in the latest issue of the journal Sleep. (ANI)

Copyright 2008 Asian News International (ANI) - All Rights Reserved.

Provided by an company
COPYRIGHT 2008 Al Bawaba (Middle East) Ltd.
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2008 Gale, Cengage Learning. All rights reserved.

Article Details
Printer friendly Cite/link Email Feedback
Publication:Asian News International
Date:Dec 3, 2008
Previous Article:Viagra does wonders for 'flagging' Christmas trees too!
Next Article:Coffee gives men a bigger buzz than women.

Related Articles
PAHs and cognitive impairment: prenatal exposure catches up with toddlers.
Effect of prenatal exposure to airborne polycyclic aromatic hydrocarbons on neurodevelopment in the first 3 years of life among inner-city children.
Prenatal meth exposure 'causes abnormal brain development in kids'.
Prenatal air pollution exposure reduces kids' IQs in later life.
Kids 'sleep badly' if mother drank during pregnancy.
Unintended pregnancy linked to unhealthy maternal behaviors.
Do Canadian prenatal record forms integrate evidence-based guidelines for the diagnosis of a FASD?
Smoking during pregnancy may raise the risk of behaviour problems in children.
Association between GIS-based exposure to urban air pollution during pregnancy and birth weight in the INMA Sabadell cohort.

Terms of use | Privacy policy | Copyright © 2022 Farlex, Inc. | Feedback | For webmasters |