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Polyamine Cell Signaling: Physiology, Pharmacology, and Cancer Research.


Polyamine cell signaling; physiology, pharmacology, and cancer research.

Ed. by Jian-Ying Wang and Robert A. Casero.

Humana Press Inc.


490 pages




Along with the most current findings about cellular and molecular functions of polyamines, this collection includes underlying concepts and knowledge leading to the development of polyamines in therapies for cancers and other diseases. Contributors cover such topics as polyamines in signal transduction, including structure and synthetic analogs and the influence of polyamines in breast and prostrate cancer, polyamines in cellular signaling of apoptosis, carcinogenesis and cancer therapy, including for NSAID-induced injury and the use of polyamine pools in cancer prevention, polyamines in cell motility and cell-to-cell interactins, including using a polyamine bloc of Kir channels, and closing with polyamine homeostasis and transport, including evidence for a multistep model for eukaryotic polyamine transport and bacterial transport systems.

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Publication:SciTech Book News
Article Type:Book Review
Date:Sep 1, 2006
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