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Pharmaceuticals.

Pharmaceuticals: Drug candidates are usually small molecules. But small molecules' size can be disadvantageous, resulting in ineffective interactions with larger molecules and lack of specificity. Macromolecule drugs, or drugs made from proteins, peptides and nucleic acids, promise more effective, specific interactions. However, they are hard to get into the body and through a cell's membrane. New solutions are tackling this problem and being tested using insulin. The gene pill from Genteric inserts a gene into cells. Other methods target the lungs. Inhalation could be used as the entrance of antisense drugs into the body. Antisense drugs interfere with mRNAs, providing improved accuracy. EpiGenesis is working on a nucleic acid to be absorbed by lung cells.

Source: The Economist
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Title Annotation:macromolecule drugs
Publication:Instrument Business Outlook
Article Type:Brief Article
Geographic Code:1USA
Date:Oct 15, 2001
Words:118
Previous Article:Environmental.
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