Pediatric weight loss. (Clinical Capsules).
While taking valproate, olanzapine, risperidone, or quetiapine for bipolar disorder and psychosis, 15 of 19 patients lost weight with metformin, a drug normally prescribed for patients with noninsulin-dependent diabetes to control blood sugar levels; 1 patient had no change in weight, while 3 others gained no more than 1.6 kg. Patients were restricted from changing their diet or level of physical activity during the course of the study (Am. J. Psychiatry 159:655-57, 2002).
At 4 weeks, all 19 patients had lost a mean of 0.93 kg. At 8 weeks, 16 patients who remained in the study lost a mean of 1.05 kg. By the end of the 12-week trial, the 12 remaining patients lost a mean of 2.93 kg and had decreased their body mass index by a mean of 2.22 kg/[m.sup.2].
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|Publication:||Clinical Psychiatry News|
|Article Type:||Brief Article|
|Date:||Jun 1, 2002|
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