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Pattern baldness linked to prostate cancer risk.

Men with a certain type of male pattern baldness in their 40s may be at increased risk of aggressive prostate cancer later in life, suggests a study published online Sept. 15 in the Journal of Clinical Oncology.

The study included more than 39,000 participants (ages 55 to 74) in a large prostate cancer screening trial who were queried about their hair-loss patterns when they were age 45. During a nearly three-year follow-up period, 1,138 prostate cancers were diagnosed, more than half of which were aggressive: Gleason score of 7 or higher, stage 3 or 4 cancer, or fatal prostate cancer.

The researchers found that men who reported having baldness at the front of their head and moderate baldness on the crown of their head at age 45 were 40 percent more likely than men who had no baldness to develop aggressive prostate cancer. The investigators found no association between other types of baldness and prostate cancer.


Further studies are necessary to confirm the findings, the researchers noted. In the meantime, men with male pattern baldness may need to be followed more closely for prostate cancer, a Cleveland Clinic expert says.

"The study suggests two things," says Eric A. Klein, MD, chairman of Cleveland Clinic's Glickman Urological & Kidney Institute. "First, the genes that cause baldness are located near a gene or genes that cause aggressive prostate cancer. Second, bald men should be screened for prostate cancer regularly since they may be at increased risk of aggressive disease."

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Title Annotation:Headlines & Your Health
Publication:Men's Health Advisor
Date:Dec 1, 2014
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