Pathogen may be stronger, more resistant.
Researchers in Canada looked into the unusual frequency and severity of hospital-acquired diseases and unexpected community-acquired outbreaks. They studied 187 isolated forms of the pathogen collected from patients where it was suspected in outbreaks of C. difficile-associated disease (CDAD). About 50 percent of the isolates were found to be the strain responsible for the hospital outbreaks. The strain has a unique toxicity that may come from increased virulence and a stronger resistance to the fluoroquinolones, compared with most other strains.
The researchers also looked at a CDAD epidemic in Montreal, where more than 1,700 instances of infection were found. In that case, 132 of the 157 collected isolates were the new, more virulent strains.
(Source: New England Journal of Medicine, 2005;353:2433-2441.)
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|Title Annotation:||MEDICAL NEWS FROM AROUND THE WORLD|
|Publication:||Nutrition Health Review|
|Article Type:||Brief article|
|Date:||Mar 22, 2005|
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