Pall launches Allegro STR 1000 bioreactor.
Pall has introduced the Allegro STR 1000 single-use, 1000 L stirred tank reactor to provide scalable cell culture performance. The Allegro STR 1000 was designed to offer cell culture process assurance, with packaging, installation, operational, quality, and regulatory needs considered from the start. Installation is largely automated with an easy-to-use operating system and requires minimal operator manipulation, according to the company.
The cubical design and large bottom-driven impeller allow high oxygen transfer rates and shorter mixing times, according to the company. Mixing mass transfer, cell culture performance and computational fluid dynamics data indicate that the Allegro STR 1000 allows for good cell culture performance for a range of mammalian cell culture processes. Also, both disposable and reusable sensors can be integrated with the Allegro STR 1000 bioreactor for increased flexibility.
The Pall Allegro STR 1000 bioreactor system is designed to industry standards for manufacturing, electronic records, and electrical equipment. The biocontainers for the Allegro STR 1000 are integrity tested during manufacture and made of transparent, low extractable Allegro film that has been characterized for extractables and leachables. Customization of the bioreactor system, from small changes in the biocontainer to integrating the bioreactor with all surrounding unit operations into a fully automated process, is also available.