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PA-457.

PA-457: A possible new kind of drug called a "maturation inhibitor" interrupts the HIV life cycle at a late step, causing "immature" (non-infectious) viruses to be produced. These harmless HIV particles are then just broken down in the body, without infecting T cells. More safety information is needed before this drug can be tested in large numbers of people, but so far the side effects seem minimal. This agent would be in pill form and would have to be taken in combination with other meds. (Abstracts 159 & 551)
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Title Annotation:maturation inhibitor
Publication:HIV Treatment: ALERTS!
Article Type:Brief Article
Date:Apr 1, 2005
Words:88
Previous Article:TMC 114.
Next Article:Tipranavir.
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