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Open dismembered pyeloplasty for uretero-pelvic junction obstruction By: Shahnawaz Shahzad Ali Iqbal Shahzad and Muhammad Umar Baloch.

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ABSTRACT Objective: To report our experience with open dismembered pyeloplasty for uretero-pelvic junction obstruction.Methods: Retrospective study was conducted in the Department of Urology Jinnah Postgraduate Medical Centre Karachi for a period of five and half years from May 2006 to December 2011. All patients with uretero-pelvic junction obstruction were entered into a database to record patients clinical features diagnostic tools operative and post-operative details and follow-up. Over a five-years period 13 procedures were performed. After clinical evaluation all patient had extensive haematological and radiological workup for diagnosis of uretero-pelvic junction obstruction. All were subjected to open pyeloplasties out of these13 patients; one had an aberrant lower pole vessel compressing uretero-pelvic-junction. All procedures were stented. Repair was done with 3/0 vicryl sutures all patients were catheterized and wound drained. Results: Mean operating time was 60 100 minutes with about 100cc blood loss requiring no transfusion. The mean follow up was one year. One patient developed post-operative haematuria and was managed conservatively. Two patients developed fever secondary to urinary tract infection despite adequate treatment of urinary tract infection according to culture and sensitivity pre-operatively. One patient developed surgical emphysema detected post-operatively which required tube thoracostomy. Neither patient developed recurrent symptoms nor had any evidence of obstruction on the renogram on follow-up. Objectively all patients were followed up by intravenous urogram stress renogram Urine C/S. Subjective and objective follow-up revealed success in 100% of patients whereas success is defined as no or minimal holder on DTPA renogram improving renal function and decreasing dilatation on successive intravenous urogram. All patients had a mean post-operative hospital stay of 02 04 days Folley catheter was removed after 10-days double-j- stents were removed after two to three weeks.Conclusion: Our success rate following open pyeloplasty with limited follow-up was 100%. It is comparable with International data. Recent international trend is toward Uretro-pelvic Junction Obstruction (UPJO) repair with laparoscopic approach they are claiming success rate of 95%.

KEY WORDS: Uretero-pelvic Junction Obstruction Open Pyeloplasty IVU DTPA.


The surgical management of uretero-pelvic junction obstruction has undergone revolutionary changes over the past few years. Traditionally open retroperitoneal dismembered reduction pyeloplasty has been considered as the treatment of choice for uretero-pelvic junction obstruction with high success rates of over 95%.1 However the procedure requires a longer flank incision and an associated longer recovery period.1 Endopyelotomy became popular in the late 1980's and early 1990's as a minimally invasive technique with lower complication rates relatively shorter operating times and quick recovery.1The success rates quoted in literature range be- tween 63% to 93%2-4 in well-selected patients. Ex- cellent success rates have been found in patients with a smaller pelvis and in whom no crossing vessels were present. By the end of the last decade laparoscopic pyeloplasty made its place and is now becoming popular day by day. Success rates are repoted in between 87100%.235-9 The procedure al- lows the identification of crossing vessels excision of the pathological uretero-pelvic junction segment a reduction pyeloplasty and a water tight anas- tomosis over a stent. In addition there is less pain with short hospital stay and a quick recovery pe- riod.1 However the procedure requires skill a long learning curve and involves longer operating times as compared to open and minimally invasive tech- niques. Laparoscopic pyeloplasty can be performed via a retroperitoneal or transperitoneal approach. Equivalent success rates have been quoted in the lit- erature.58-11 We analysed the data of all open pyelo- plasty were performed since 2006 to report our ex- perience and the successful outcome we achieved.


All patients presenting to our institution with uretero-pelvic junction obstruction after May2006 are entered into a database. Patients details operative information and post-operative follow up were recorded.Over this five-year period a total of 13 procedures were performed for uretero-pelvic junction obstruction. All procedures were open retroperitoneal dismembered reduction pyeloplasties performed by single surgeon. One (01) patient had a double-j-stent inserted initially as temporary measure pre-operatively.There were 08 males and 05 females (male to female ratio 8:5) included in this study. The left kidney was most commonly affected. Loin pain was the predominant presenting symptom in 76.9% with 15.38% presenting with recurrent urinary tract infections and 7.69% presented with haematuria. Three patients (23.07%) were also noted to have concurrent renal calculi pre-operatively. The mean age at the time of operation was 22 (1635) years. Open dismembered reduction pyeloplasty technique:Preparation and positioning: A decision about the need for pre-operative retrograde pyelography is always made on individual basis. A folley catheter is placed in the bladder and the patient positioned with the affected side up to make a lumber subcos- tal / 12th rib approach whatever required. Procedure: The retroperitoneal space was initially developed by blunt dissection to push the perito- neum away. The ureter was identified and traced upto the uretero-pelvic junction.Kidney and proximal ureter were mobilized taking care not to damage blood supply of proximal ureter. Once uretero-pelvic junction was exposed fine stay sutures were placed at the anterior portion of proximal ureter so that it might not twist and at the upper and lower ends of pelvis. The proximal ureter was then transected above the marking suture. The renal pelvis was transected similarly in a diamond shape manner. Now the obstructed UPJ was separated out. Repair was carried out using3/0 vicryl interrupted sutures. We did reduction of the renal pelvis in all cases. Aberrant lower pole vessel found in one case as the cause of external compression was not disturbed. Rather UPJ repair was done posterior to it. Anastomosis was always stented with double-j-stent and perinephric space was also always drained. Folley was also inserted. Postoperative care: The drain was removed on the3rd postoperatve day and folley catheter is usually removed on the tenth postoperative day. The stent is removed in two to three weeks' time. An F-15 diuretic MAG-3 renogram is performed at 3 and12 months and annually thereafter. When this is equivocal an IVU is performed and urine culture sensitivity is done.Success is defined as no or minimal hold-up on DTPA renogram improving renal function and decreasing dilatation on successive intravenous urogram.


All the 13 patients underwent open dismembered reduction pyeloplasty. Twelve (92.30%) patients were treated primarily with pyeloplasty and one patient treated with double-j-stent upon her choice after adequate counselling but eventually procedure of pyeloplasty was done.

Table-I: Open dismembered reduction pyeloplasty.

No. of patients (n=13)



Age years (range) 22 (1635)

Side of kidney:



Table-II: Peri-operative details for open retroperitoneal

###dismembered reduction pyeloplasty.

###Mean operative time / mins (range)###80 (80 100)

###Mean post-op stay / days (range)###3.0 (2 4)

###Pre-op function/% (range)###33 (20 54%)

###Post-op function/% (range)###35 (17 56%)

###Mean follow-up / months (range)###24

###Success rate/n (%)###13 (100%)

There were 08 males and 05 females (male to female ration 8:5) included in the study. The left kidney was most commonly affected. Loin pain was the predominant presenting symptom in 76.9% the recurrent urinary tract infections in 15.38% and haematuria in 7.69%. Three patients (23.07%) were also noted to have concurrent secondary renal calculi pre-operatively. The mean age at the time of operation was 22 (1635) years +6.The mean operative time was 60100 minutes. Two (15.38%) patients developed fever and urinary tract infection although had an adequate per-operative antibiotic coverage according to culture and sensitivity. One (7.69%) patient developed haematuria which was conservatively managed. One (7.69%) patient developed surgical emphysema which was detected post-operatively and a tube thoracostomy was made. None of our patients developed recurrence even after two years of follow-up. The Radio-nuclide stress renogram urine C/S and intravenous urogram / ultrasonography and renal function profile were used to record improvement in all of our patients.This is in accordance to different institutions database the success rate for open pyeloplasty at their institution is 95-97% with a mean follow-up of48 months and the mean post-operative stay is (2 4) days.None of the patients in our series developedrecurrence or failure. We believe that this couldbe due to small size of the study and probably alonger followup might further enlighten our highersuccess rate.


No doubt greater than 90% success rate have been observed with gold standard surgical approaches whether it be open or laparoscopic pyeloplasty for uretero-pelvic junction obstruction.12 Traditional transanastomotic stenting also acting as a nephrostomy tube drainage of the kidney has been replaced by doublej-stenting of the uretero pelvic junction.13 Although non stented pyeloplasty has been used in paediatric patients with similar results to stented pyeloplasty.14 In third world countries like Pakistan laparoscopicaly is not yet performed frequently. Therefore we performed open dismembered reduction pyeloplasty in our tertiary care referral centre.Reviewing our more than five years data of open dismembered pyeloplasties a success rate of 100% is seen at a mean follow-up of 12 months. Whereas success is defined as no or minimal holdup on DTPA renogram improving renal function and decreasing dilatation on successive intravenous pyelograms. It is equivalent to that seen with other international open pyeloplasty series.1 Our mean follow-up is short; however other series report that failures following open retroperitoneal pyeloplasty tend to occur within the first post-operative year.6The mean operative time for our series patients was 80 minutes; however it varied between 60-130 minutes with majority of cases finishing by 80 minutes. Mean operating time in different institutions varies from 60 100 minutes. Our institution is dedicated to teaching trainees and this may further add to longer operative time in few cases. In addition all of our patients required a reduction pyeloplasty thus increasing operative time. According to national and internationalliterature almost equivalent success rates (95 100%) are reported for this procedure.58-11 Only one patient had an aberrant crossing vessel to lower pole compressing uretero-pelvic-junction. The main advantage with the open retroperitoneal approach is the reduced risk of bowel injury nd the better familiarity of retro peritoneum o urologists. Crossing vessels may be easily visualised the anastomosis may be transposed to other retroperitoneal procedures like open pyelolithotomy and retroperitoneal nephrectomies and then exposed to open retroperitoneal pyeloplasties. Experience reduces complications and the time duration of the procedure and success rate also increases.The disadvantages include large access wound weak postoperative muscle strength mimicking hernia difficulties with orientation and limited space which can be multiplied by excessive retroperitoneal fats. Suturing can be difficult especially with inadequate lateral positioning of the patient.1 Several authors including us have reproduced the high success rates achieved with open surgery with low morbidity and early discharge from the hospital.1516Advances in equipment and technique have resulted in technique shift in the favour of laparoscopic pyeloplasty. The main argument against laparoscopic reconstructive procedures is because laparoscopic suturing is challenging time consuming and is associated with prolonged learning curve.16Regarding laparoscopic procedures we are still in learning phase hopefully in near future we will be able to perform laparoscopic pyeloplasty and compare our results with open technique. Our study has some limitation like shorter follow- up small sample size overage group and non- laparoscopic pyeloplasty surgical technique.


Overall our success rate following open retroperitoneal dismembered reduction pyeloplasty is 100% which is equivalent to that seen from other Centres with the additional benefits of reduced hospital stay. Regarding laparoscopy we are still in learning phase hopefully in near future we will be able to perform both open and laparoscopic pyeloplasty at our Centre and would be able to compare our results accordingly.


1. Bauer JJ Bishoff JT Moore RG Chen RN Iverson AJ Kavoussi LR. Laparoscopic versus open pyeloplasty: assessment of objective and subjective outcome. J Urol.1999;162(3Pt1):692-695.2. Parkin J Evans S Kumar PVS Timoney AG Keeley Jr. FX.Endoluminal ultrasound before retrograde endopyelotomy:Can the results match laparoscopic pyeloplasty BJU Int.2003;91(4):389-391.3. Pardalidis NP Papatsoris AG Kosmaoglou EV. Endoscopicand laparoscopic treatment of uretero-pelvic junctionobstruction. J Urol. 2002;168(5):19371940. 4. Albani JM Yost AJ Streem SB. Uretero-pelvic junction obstruction: determining durability of endourological intervention. J Urol. 2004;171(2Pt 1):579-582.5. Eden CG Cahill D Allen JD. Laparoscopic dismembered pyeloplasty: 50 consecutive cases. BJU Int. 2001;88(6):526-531.6. Jarrett TW Chan DY Charambura TC Fugita D KavoussiLR. Laparoscopic pyeloplasty. The first 100 cases. J Urol.2002;167(3):12531256.7. Turk IA Davis JW Winklemann B Deger S Richter RFabrizio MD et al. Laparoscopic dismembered pyeloplasty.The method of choice in the presence of an enlarged renalpelvis and crossing vessels. Eur Urol. 2002;42(3):268-275.8. Soulie M Salomon L Patard JJ Mouly P ManutaA Antiphen P et al. Extraperitoneal laparoscopicpyeloplasty: A multicentre study of 55 procedures. J Urol.2001;166(1):4850.9. Hemal AK Goel R Goel A. Cost effective laparoscopicpyeloplasty: Single centre experience. Int J Urol.2003;10(11):563568.10. Deger S Roigas J Wille A Giessing M Schonberger B TurkIA. Laparoscopic dismembered pyeloplasty with Anderson-Haynes technique. Urologe A. 2003;42(3):347353.11. Gnanapragasam VJ Armitage TG. Laparoscopicpyeloplasty initial experience in the management of UPJO.Ann R Coll Surg Eng. 2001;83(5):347352.12. Ozdemir T Arikan A. One day hospitalization afteropen double-J-stented pyeloplasty. World J Paediatr.2010;6(3):271-272.13. Chandrasekharam VV. Is reterograde stenting more reliablethan antegrade stenting for pyeloplasty in infants andchildren Urology. 2005;66:1301-1304.14. Smith KE Holmes N Leib JI Mandell J Baskin LS KoganBA et al. Stented versus non-stented paediatric pyeloplasty:A modern series and review of the literature. J Urol.2002;168:1127-1130.15. Yanke BV Lallas CD Pagnam C. The minimally invasivetreatment of uretero-pelvic-junction obstruction: areview of our experience during the last decade. J Urol.2008;180:1397-1402.16. Piaggio LA Guimond JF Noh PH. Transperitoneallaparoscopic pyeloplasty for primary repair of uretero-pelvic-junction obstruction in infants and children:comparison with open surgery. J Urol. 2007;178:1579-1583.
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Publication:Pakistan Journal of Medical Sciences
Date:Feb 28, 2014
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